Immune Profile after Autologous Hematopoietic Stem Cell Transplantation for Autoimmune Diseases: Where Do We Stand?

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Release : 2020-02-12
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Book Rating : 728/5 ( reviews)

Immune Profile after Autologous Hematopoietic Stem Cell Transplantation for Autoimmune Diseases: Where Do We Stand? - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Immune Profile after Autologous Hematopoietic Stem Cell Transplantation for Autoimmune Diseases: Where Do We Stand? write by Kelen Cristina Ribeiro Malmegrim. This book was released on 2020-02-12. Immune Profile after Autologous Hematopoietic Stem Cell Transplantation for Autoimmune Diseases: Where Do We Stand? available in PDF, EPUB and Kindle. Autologous hematopoietic stem cell transplantation (AHSCT) was proposed 20 years ago as an alternative therapeutic approach for patients with severe and refractory autoimmune diseases. Since then, this innovative therapy has been successfully used to treat several autoimmune diseases, such as neurological disorders (Multiple Sclerosis), connective tissue diseases (Systemic Sclerosis and Systemic Lupus Erythematous), gastrointestinal inflammatory diseases (Crohn’s Disease) and others (Juvenile Arthritis, Type 1 Diabetes, Vasculitis). Experience in phase I-II and III clinical trials over the years has led to increased safety and efficacy of this procedure. Recent studies have demonstrated superior therapeutic efficacy of AHSCT versus conventional therapies, showing that transplantation can induce long-term disease remission in the absence of any further immunosuppressive treatment. Immune monitoring studies have showed that AHSCT is able to reduce the inflammatory milieu, to reset the immune balance and to promote the generation of a new auto-tolerant immune repertoire. However, some patients fail to remain in remission, and disease is re-activated after some time post-transplantation. This scenario indicates that further immunological interventions may be still required to improve AHSCT efficacy. Clear understanding of the operating immune mechanisms that contribute to specific clinical outcomes is vital to enable improvement of AHSCT protocols for autoimmune diseases.

The European Blood and Marrow Transplantation Textbook for Nurses

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Release : 2018-03-14
Genre : Medical
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Book Rating : 260/5 ( reviews)

The European Blood and Marrow Transplantation Textbook for Nurses - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The European Blood and Marrow Transplantation Textbook for Nurses write by Michelle Kenyon. This book was released on 2018-03-14. The European Blood and Marrow Transplantation Textbook for Nurses available in PDF, EPUB and Kindle. This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Thomas' Hematopoietic Cell Transplantation

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Release : 2015-12-14
Genre : Medical
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Book Rating : 120/5 ( reviews)

Thomas' Hematopoietic Cell Transplantation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Thomas' Hematopoietic Cell Transplantation write by Stephen J. Forman. This book was released on 2015-12-14. Thomas' Hematopoietic Cell Transplantation available in PDF, EPUB and Kindle. Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.

The EBMT Handbook

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Release : 2020-10-08
Genre : Medical
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Book Rating : 674/5 ( reviews)

The EBMT Handbook - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The EBMT Handbook write by Nicolaus Kröger. This book was released on 2020-10-08. The EBMT Handbook available in PDF, EPUB and Kindle. This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Manual of Stem Cell and Bone Marrow Transplantation

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Release : 2013-10-17
Genre : Medical
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Book Rating : 544/5 ( reviews)

Manual of Stem Cell and Bone Marrow Transplantation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Manual of Stem Cell and Bone Marrow Transplantation write by Joseph H. Antin. This book was released on 2013-10-17. Manual of Stem Cell and Bone Marrow Transplantation available in PDF, EPUB and Kindle. The fully revised second edition is a practical manual for all members of the stem cell and bone marrow transplant team.