Immunogenomics and Human Disease

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Release : 2006-03-30
Genre : Science
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Book Rating : 24X/5 ( reviews)

Immunogenomics and Human Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Immunogenomics and Human Disease write by Andras Falus. This book was released on 2006-03-30. Immunogenomics and Human Disease available in PDF, EPUB and Kindle. This book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology, autoimmunity, allergy and the response to infection.

Human Immunogenetics

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Release : 2020-10-28
Genre : Health & Fitness
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Book Rating : 730/5 ( reviews)

Human Immunogenetics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Human Immunogenetics write by S. D. Litwin. This book was released on 2020-10-28. Human Immunogenetics available in PDF, EPUB and Kindle. Delineating fundamental concepts of contemporary immunogenetics, this reference/text examines specific immunogenetic systems in terms of molecular biochemistry and immunophysiology. Covers material in diverse fields, including infectious diseases, cell biology, virology, molecular genetics. Comprise

Immunogenetics of Autoimmune Disease

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Release : 2007-12-22
Genre : Medical
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Book Rating : 267/5 ( reviews)

Immunogenetics of Autoimmune Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Immunogenetics of Autoimmune Disease write by Jorge R. Oksenberg. This book was released on 2007-12-22. Immunogenetics of Autoimmune Disease available in PDF, EPUB and Kindle. utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion molecules, growth factors, antibodies, and other molecules induce and regulate critical cell functions that perpetuate inflammation, leading to tissue injury and clinical phenotype. The nature and intensity of this response as well as the physiological ability to restore homeostasis are to a large extent conditioned by the unique amino acid sequences that define allelic variants on each of the numerous participating mol ecules. Therefore, the coding genes in their germline configuration play a primary role in determining who is at risk for developing such disorders, how the disease progresses, and how someone responds to therapy. Although genetic components in these diseases are clearly present, the lack of obvious and homogeneous modes of transmission has slowed progress by prevent ing the full exploitation of classical genetic epidemiologic techniques. Furthermore, autoimmune diseases are characterized by modest disease risk heritability and m- tifaceted interactions with environmental influences. Yet, several recent discoveries have dramatically changed our ability to examine genetic variation as it relates to human disease. In addition to the development of large-scale laboratory methods and tools to efficiently recognize and catalog DNA diversity, over the past few years there has been real progress in the application of new analytical and data-manage ment approaches.

Immunogenetic Risk Assessment in Human Disease

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Release : 1995
Genre : Medical
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Book Rating : 157/5 ( reviews)

Immunogenetic Risk Assessment in Human Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Immunogenetic Risk Assessment in Human Disease write by Janardan P. Pandey. This book was released on 1995. Immunogenetic Risk Assessment in Human Disease available in PDF, EPUB and Kindle. Recent findings have increased our understanding of HLA and the immunoglobulin allotypes Gm and Km, and their role in the genetic control of immune responsiveness and susceptibility to disease. These significant discoveries, which were presented at the international conference on Immunogenetic Risk Assessment in Human Disease held in Charleston, S.C., in March 1994, are now featured in this special issue. Some of the contributions discuss modern molecular methods for the detection of these polymorphic systems as well as their influence on the predisposition to various human diseases - especially autoimmune and infectious diseases. Other articles review biometrical methods employed to identify genes implicated in human diseases. Furthermore, possible reasons for the evolution of the extensive polymorphism of HLA and Gm systems are given. This fascinating publication on two important gene complexes of the human immune system will be of great value to scientists working in the fields of immunology, and immunogenetics, human genetics, genetic epidemiology, population genetics and physical anthropology.

Immunogenetics: A Molecular and Clinical Overview

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Release : 2021-11-30
Genre : Medical
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Book Rating : 355/5 ( reviews)

Immunogenetics: A Molecular and Clinical Overview - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Immunogenetics: A Molecular and Clinical Overview write by Muneeb U. Rehman. This book was released on 2021-11-30. Immunogenetics: A Molecular and Clinical Overview available in PDF, EPUB and Kindle. A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. Contains exclusive information about research on immunogenetics from around the globe Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner