Inflammatory and Autoimmune Disorders of the Nervous System in Children - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Inflammatory and Autoimmune Disorders of the Nervous System in Children write by Russell C. Dale. This book was released on 2010-01-19. Inflammatory and Autoimmune Disorders of the Nervous System in Children available in PDF, EPUB and Kindle. Inflammatory disorders of the nervous system, although individually uncommon, collectively make up 10-20% of acute paediatric neurology presentations and many are potentially treatable. Research into them is lagging behind adult research, but better diagnosis and often simple treatments could lead to substantial clinical benefit and reduction in long-term disability. This book provides a detailed and comprehensive summary of the childhood diseases that are, or are likely to be, caused by the immune system. The authors not only describe these disorders and their treatments comprehensively, helping pediatricians and pediatric neurologists to improve their understanding and recognition of the conditions, but also highlight recent and exciting developments that will be of considerable importance in the future.
Pediatric Neurology
Pediatric Neurology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pediatric Neurology write by Daniela. Pohl. This book was released on 2013-04-23. Pediatric Neurology available in PDF, EPUB and Kindle. Systemic disorders with possible involvement of the nervous system include a variety of diseases with presumed inflammatory and autoimmune pathomechanisms, among them Behçet disease, sarcoidosis, systemic lupus erythematosus, juvenile idiopathic arthritis, scleroderma, and Sjögren syndrome. This disease group encompasses systemic inflammatory disorders with a genetically defined dysregulation of the innate immune system as well as systemic autoimmune disorders characterized by alterations of the adaptive immunity such as autoantibodies and autoreactive T cells. Although more commonly diagnosed in adults, all of these diseases can manifest in childhood and some as early as infancy. Neurological involvement may represent the initial manifestation, and nearly every neurological symptom can be caused by inflammatory/autoimmune diseases. In a child with (sub)acute onset of otherwise unexplained neurological findings, consideration of inflammatory/autoimmune disorders may be of crucial therapeutic and prognostic importance. In the absence of disease-specific clinical features, the initial diagnostic workup is broad. Basic blood tests include inflammatory markers and autoantibodies. Cerebral magnetic resonance imaging and a lumbar puncture with measurement of opening pressure as well as cerebrospinal fluid analysis are indicated in most patients with central nervous system (CNS) involvement. Skin, muscle, or organ biopsies (e.g., renal) may provide additional information. Especially in patients with isolated CNS involvement, a brain biopsy may be indicated. Timely recognition and treatment of CNS inflammation may improve or even reverse clinical symptoms and prevent secondary brain injury.
Immune-mediated Disorders of the Central Nervous System in Children
Immune-mediated Disorders of the Central Nervous System in Children - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Immune-mediated Disorders of the Central Nervous System in Children write by Lucia Angelini. This book was released on 2002. Immune-mediated Disorders of the Central Nervous System in Children available in PDF, EPUB and Kindle. Immunopathogenesis has recently been receiving increased interest from researchers, leading to a better understanding of the mechanisms of neurological disorders and consequently to new diagnostic approaches and therapeutic perspectives. Clinical neuroimmunology in childhood is the focus of the present volume. This book is divided into three sections. The first part deals with the relationship between the immune and the nervous systems, from antigen presentation to autoimmunity and its role in neurological disease. In the second part, the nosography of immune-mediated neurological diseases in children is described, including those primarily involving the central nervous system and those secondary to systemic immunological disorders. The last part of the book is devoted to diagnostic and therapeutic criteria.
Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics
Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics write by Emmanuelle Waubant. This book was released on 2017-11-07. Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics available in PDF, EPUB and Kindle. This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.
Autoimmune Neurology
Autoimmune Neurology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Autoimmune Neurology write by . This book was released on 2016-03-11. Autoimmune Neurology available in PDF, EPUB and Kindle. Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities
