Interplay between Metal Ions and Nucleic Acids - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Interplay between Metal Ions and Nucleic Acids write by Astrid Sigel. This book was released on 2012-01-02. Interplay between Metal Ions and Nucleic Acids available in PDF, EPUB and Kindle. Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics.
Metal Ions in Biological Systems
Metal Ions in Biological Systems - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Metal Ions in Biological Systems write by Astrid Sigel. This book was released on 1996-02-05. Metal Ions in Biological Systems available in PDF, EPUB and Kindle. Volume 32 covers metal ion bonding to phosphate, sugar and nucleobase residues; the ambidentate as well as the stacking properties of nucleotides; kinetic aspects as well as properties of nucleobase and nucleotide analogs; and the oligonucleotides and nucleic acids. It examines electron transfer reactions over a large number of base repairs in DNA, the role of metal ions in ribozymes, ternary metal-nucleic acid base-protein complexes, metal responsive gene regulation, and the structure-activity relationships of anticancer drugs and their action on DNA, including cisplatin and the role of proteins.
Nucleic Acid-metal Ion Interactions
Nucleic Acid-metal Ion Interactions - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Nucleic Acid-metal Ion Interactions write by Nicholas V. Hud. This book was released on 2009. Nucleic Acid-metal Ion Interactions available in PDF, EPUB and Kindle. Provides a perspective on nucleic acid-metal ion interactions with an emphasis on experimental biophysical studies which will prove indispensable to biophysicists and molecular biologists.
Interplay Between Metal Ions and Nucleic Acids
Interplay Between Metal Ions and Nucleic Acids - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Interplay Between Metal Ions and Nucleic Acids write by Astrid Sigel. This book was released on 2012-01-02. Interplay Between Metal Ions and Nucleic Acids available in PDF, EPUB and Kindle. Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics.
Metal Complex - DNA Interactions
Metal Complex - DNA Interactions - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Metal Complex - DNA Interactions write by Nick Hadjiliadis. This book was released on 2009-03-30. Metal Complex - DNA Interactions available in PDF, EPUB and Kindle. Metal ions and metal complexes have long been recognized ascritically important components of nucleic acid chemistry, both inregulation of gene expression and as promising therapeutic agents.Understanding how metal complexes interact with DNA has become anactive research area at the interface between chemistry, molecularbiology and medicine. Metal Complex - DNA Interactions provides a comprehensiveoverview of this increasingly diverse field, presenting recentdevelopments and the latest research with particular emphasis onmetal-based drugs and metal ion toxicity. The text is divided intofour parts: Basic Structural and Kinetic Aspects: includes chapterson sequence-selective metal binding to DNA and thermodynamicmodels. Medical Applications: focuses on anticancer platinumdrugs, including discussions on DNA repair in antitumor effects ofplatinum drugs and photo-dynamic therapy. DNA-Recognition - Nucleases and Sensor: describesprobes for DNA recognition, artificial restriction agents,metallo-DNAzymes for metal sensing applications and metal iondependent catalysis in nucleic acid enzymes. Toxicological Aspects: deals with structural studies ofmercury–DNA interactions, chromium-induced DNA damage andrepair, and the effect of arsenic and nickel on DNAintegrity. This book will be a valuable resource for academic researchersand professionals from a range of pharmaceutical and chemicalindustries, particularly those involved in the development of newand less toxic anticancer metallo-drugs, and in the field ofenvironmental and toxicological chemistry.
