Intestinal Microbiota Influence Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation and Intestinal GVHD - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Intestinal Microbiota Influence Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation and Intestinal GVHD write by Natalie Köhler. This book was released on 2019. Intestinal Microbiota Influence Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation and Intestinal GVHD available in PDF, EPUB and Kindle.
Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation
Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation write by Dominik Schneidawind. This book was released on 2020-05-22. Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation available in PDF, EPUB and Kindle.
Fecal Microbiota Transfer for Refractory Intestinal Graft-versus-host Disease -- Experience from Two German Tertiary Centers
Fecal Microbiota Transfer for Refractory Intestinal Graft-versus-host Disease -- Experience from Two German Tertiary Centers - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Fecal Microbiota Transfer for Refractory Intestinal Graft-versus-host Disease -- Experience from Two German Tertiary Centers write by Felix Goeser. This book was released on 2021. Fecal Microbiota Transfer for Refractory Intestinal Graft-versus-host Disease -- Experience from Two German Tertiary Centers available in PDF, EPUB and Kindle. Rationale: Steroid refractory graft-vs-host disease (sr-GvHD) represents a challenging complication after allogeneic hematopoietic cell transplantation (allo-HCT). Intestinal microbiota (IM) diversity and dysbiosis were identified as influencing factors for the development of acute GvHD. Fecal microbiota transfer (FMT) is hypothesized to restore IM dysbiosis, but there is limited knowledge about the significance of FMT in the treatment of sr-GvHD. Objectives: We studied the effects of FMT on sr-GvHD in allo-HCT patients from two German tertiary clinical centers (n = 11 patients; period: March 2017 until July 2019). To assess safety and clinical efficacy, we analyzed clinical data pre- and post-FMT (day -14 to +30 relative to FMT). Moreover, IM were analyzed in donor samples and in a subset of patients pre- and post-FMT by 16S rRNA sequencing. Results: Post-FMT, we observed no intervention-associated, systemic inflammatory responses and only minor side effects (5/11 patients: abdominal pain and transformation of peristalsis--each 3/11 and vomiting--1/11). Stool frequencies and volumes were significantly reduced [pre- vs post-FMT (d14): P
Contemporary Bone Marrow Transplantation
Contemporary Bone Marrow Transplantation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Contemporary Bone Marrow Transplantation write by Mammen Chandy. This book was released on 2021-03-25. Contemporary Bone Marrow Transplantation available in PDF, EPUB and Kindle. Bone Marrow transplantation or Hematopoietic stem cell transplantation is a life saving procedure in a number of diseases,hematological and non hematological, which fail alternative medical management or have no other treatment options. It has transformed the lives of thousands of patients and their families around the world battling with fatal or debilitating diseases.There are many unique aspects of bone marrow transplantation which makes it very different from solid organ transplants. There is an enormous amount of research going on in this field both at clinical and basic science levels.With the rapidly changing world and field of transplantation, there is a need for an authoritative and up to date resource for transplant professionals. This book titled Contemporary Bone Marrow Transplantation aims to be a reference text comprehensively covering various facets of hematopoietic stem cell transplants with latest insights about the technique and basic science behind it . The book is the product of collective effort of transplant professionals round the world, and will reflect their experience as well as the current standard of care practices in Stem cell transplantation.The book will be divided into different sections focusing on the basic science of bone marrow transplant, the technical aspects of the procedure itself and the supportive care of transplant patients.There will also be a section each on epidemiology, upcoming trends and also case studies , which will discuss real case scenarios from the experience of the authors, to illustrate the practical challenges in managing bone marrow transplant recipients.
Chronic Graft Versus Host Disease
Chronic Graft Versus Host Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Chronic Graft Versus Host Disease write by Georgia B. Vogelsang. This book was released on 2009-04-20. Chronic Graft Versus Host Disease available in PDF, EPUB and Kindle. Chronic graft versus host disease (GVHD) is the most common complication of allogenic bone marrow transplantation. Because of the protracted clinical course of chronic GVHD, transplant centers and hematology/oncology offices are inadequately equipped to manage these immuno-incompetent patients with a multi-system disorder. Practitioners need to be able to recognize and effectively manage chronic GVHD as a late effect of more than half of allogenic transplantations. The text is oriented for the clinician, with chapters covering staging, organ site and system-specific manifestations, treatment options, and supportive care. Drs Georgia B. Vogelsang and Steven Z. Pavletic have been pioneers in the recognition of the multi-organ complexity of this disease and have gathered the input of a variety of subspecialist physicians for this book. This book fills the gap in practical literature on chronic GVHD, providing a comprehensive, up-to-date, and clinically relevant resource for anyone who deals with cancer patients post-transplant.
