Ion Channels and Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ion Channels and Disease write by Frances M. Ashcroft. This book was released on 1999-10-20. Ion Channels and Disease available in PDF, EPUB and Kindle. Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies. Ion Channels and Disease provides an informative and up-to-date account of our present understanding of ion channels and the molecular basis of ion channel diseases. It includes a basic introduction to the relevant aspects of molecular biology and biophysics and a brief description of the principal methods used to study channelopathies. For each channel, the relationship between its molecular structure and its functional properties is discussed and ways in which genetic mutations produce the disease phenotype are considered. This book is intended for research workers and clinicians, as well as graduates and advanced undergraduates. The text is clear and lively and assumes little knowledge, yet it takes the reader to frontiers of what is currently known about this most exciting and medically important area of physiology. Introduces the relevant aspects of molecular biology and biophysics Describes the principal methods used to study channelopathies Considers single classes of ion channels with summaries of the physiological role, subunit composition, molecular structure and chromosomal location, plus the relationship between channel structure and function Looks at those diseases associated with defective channel structures and regulation, including mutations affecting channel function and to what extent this change in channel function can account for the clinical phenotype
Ion Channel Diseases
Ion Channel Diseases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ion Channel Diseases write by . This book was released on 2011-09-06. Ion Channel Diseases available in PDF, EPUB and Kindle. Ion channel dysfunction in humans leads to impairment of the excitable processes necessary for the normal function of several tissues, such as muscle and brain. It follows that an increasing number of human diseases have been associated with malfunctioning ion channels, many of which have a genetic component. This volume of Advances in Genetics presents a broad and comprehensive overview of the inherited channelopathies in humans, including clinical, genetic and molecular aspects of these conditions. Keeping true to the scope of the serial, novel genomic and modeling research approaches and a review of potential therapeutic approaches for each of these conditions are also incorporated.
Handbook of Ion Channels
Handbook of Ion Channels - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Handbook of Ion Channels write by Jie Zheng. This book was released on 2015-02-25. Handbook of Ion Channels available in PDF, EPUB and Kindle. The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of ce
Ion Channels in Health and Disease
Ion Channels in Health and Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ion Channels in Health and Disease write by Geoffrey S. Pitt. This book was released on 2016-07-11. Ion Channels in Health and Disease available in PDF, EPUB and Kindle. Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single resource that integrates disparate areas of biology and disease ion channel biology, this publication includes cross-referencing for disease, channels, and tissues. Offers a broad view of research of interest to early and experienced researchers across biological and biomedical research. Provides an overview of fundamental concepts in ion channels research to link defects in human disease Written in an accessible manner, without jargon Provides a helpful, easy cross-reference for diseases, channels, and tissues
Textbook of Ion Channels Volume III
Textbook of Ion Channels Volume III - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Textbook of Ion Channels Volume III write by Jie Zheng. This book was released on 2023-06-28. Textbook of Ion Channels Volume III available in PDF, EPUB and Kindle. Gives newcomers to the field a foundation in ion channel properties Details up-to-date techniques used in the study of ion channels, including fluorescence spectroscopy, x-ray crystallography, and electrophysiology Links the physiology of ion channels to diseases, such as cardiovascular diseases and cystic fibrosis Includes case studies and a glossary
