Lectins and Glycobiology

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Author :
Release : 2012-12-06
Genre : Science
Kind :
Book Rating : 441/5 ( reviews)

Lectins and Glycobiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Lectins and Glycobiology write by Hans-Joachim Gabius. This book was released on 2012-12-06. Lectins and Glycobiology available in PDF, EPUB and Kindle. The intriguing complexity, precision, and regulation of the wide range of biologi cal processes is determined by intricate mechanisms of molecular recognition. Their nature is under intense scrutiny. In addition to the well-appreciated interac tion of proteins either with amino acid or nucleotide sequences, the investigation of their interplay with carbohydrate elements of cellular glycoconjugates current ly exerts increasing attraction. In the group of carbohydrate-binding proteins, lec tins are distinguished from antibodies or ligand-affecting enzymes, according to the most recent definition. The thorough analysis of their structure and function is considered as a focus to collect a critical mass of information for delineating details of a further array of biochemical processes with pivotal physiological im pact. Following an already century-long history of scientific description, reflected by subjectively chosen highlights (see the Brief History of Lectin Research at page VI), the excitement in glycobiological research that prevails today can easily be ex plained by our growing awareness of the multifarious significance of a sugar-code system of biological information. This present notion unmistakably has an im pact on lines of research in diverse disciplines like cell and molecular biology, histochemistry, or clinical sciences. It also prompts inherent practical questions such as how to obtain lectins, or how to employ them as instruments in various assay systems with the best possible results. Thus, this book is devoted intentionally to cover the techniques in different research fields that deal with lectins.

Essentials of Glycobiology

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Release : 1999
Genre : Medical
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Book Rating : 818/5 ( reviews)

Essentials of Glycobiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Essentials of Glycobiology write by Ajit Varki. This book was released on 1999. Essentials of Glycobiology available in PDF, EPUB and Kindle. Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Plant Glycobiology – a sweet world of lectins, glycoproteins, glycolipids and glycans

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Release : 2015-02-12
Genre : Botany
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Book Rating : 213/5 ( reviews)

Plant Glycobiology – a sweet world of lectins, glycoproteins, glycolipids and glycans - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Plant Glycobiology – a sweet world of lectins, glycoproteins, glycolipids and glycans write by Els J. M. Van Damme. This book was released on 2015-02-12. Plant Glycobiology – a sweet world of lectins, glycoproteins, glycolipids and glycans available in PDF, EPUB and Kindle. Plants synthesize a wide variety of unique glycan structures which play essential roles during the life cycle of the plant. Being omnipresent throughout the plant kingdom, ranging from simple green algae to modern flowering plants, glycans contribute to many diverse processes. Glycans can function as structural components in the plant cell wall, assist in the folding of nascent proteins, act as signaling molecules in plant defense responses or (ER) stress pathways, or serve within the energy metabolism of a plant. In most cases, glycans are attached to other macromolecules to form so-called glycoconjugates (e.g. glycoproteins, proteoglycans and glycolipids), but they can also be present as free entities residing in the plant cell. Next to the broad, complex set of glycans, plants also evolved an elaborate collection of lectins or proteins with a lectin-like domain, which can recognize and bind to endogenous (plants-own) or exogenous (foreign) glycans. Though still poorly understood in plants, the dynamic interactions between lectins and carbohydrate structures are suggested to be involved in gene transcription, protein folding, protein transport, cell adhesion, signaling as well as defense responses. As such, a complex and largely undetermined glycan-interactome is established inside plant cells, between cells and their surrounding matrix, inside the extracellular matrix, and even between organisms. Studying the biological roles of plant glycans will enable to better understand plant development and physiology in order to fully exploit plants for food, feed and production of pharmaceutical proteins. In this Research Topic, we want to provide a platform for articles describing the latest research, perspectives and methodologies related to the fascinating world of plant glycobiology, with a focus on following subjects: 1. Identification and characterization of plant glycans, their biosynthetic and degradation enzymes 2. Characterization of plant lectins and glycoproteins 3. Plant glycans in the plant’s energy metabolism 4. Role of plant glycans in plant defense signaling 5. Use of plant lectins in pest control 6. Plant lectins as new tools in human medicine 7. Glyco-engineering in plants

The Sugar Code

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Release : 2011-09-19
Genre : Science
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Book Rating : 946/5 ( reviews)

The Sugar Code - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Sugar Code write by Hans-Joachim Gabius. This book was released on 2011-09-19. The Sugar Code available in PDF, EPUB and Kindle. A reader friendly overview of the structure and functional relevance of natural glycosylation and its cognate proteins (lectins), this book is also one of the few books to cover their role in health and disease. Edited by one of the pioneering experts in the field and written by a team of renowned researchers this resource is a perfect introduction for all students in life and medical sciences, biochemistry, chemistry and pharmacy. Website: WWW.WILEY-VCH.DE/HOME/THESUGARCODE

Plant Lectins

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Release : 1991
Genre : Medical
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Book Rating : 241/5 ( reviews)

Plant Lectins - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Plant Lectins write by A. Pusztai. This book was released on 1991. Plant Lectins available in PDF, EPUB and Kindle. This volume surveys the chemistry, biochemistry, biosynthesis, metabolism and pharmacological properties of lectins. Lectins, which are most commonly found in plants, are widespread natural products with striking biological activities. Their specific ability to recognise and bind to simple or complex saccharides facilitates their role as effective information protein molecules. As agents of cell-to-cell recognition, lectins promote symbiosis between plants and specific nitrogen-fixing soil bacteria. As natural defensive molecules, they can protect plants against predators such as bacteria, fungi and insects. As part of our diet, lectins are powerful exogenous growth factors in the small intestine and influence our health, the digestive function and the bacterial ecology of the alimentary tract. Lectins are also important research tools in preparative biochemistry and cell science.