Mast Cells and Basophils

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Release : 2000-05-25
Genre : Medical
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Book Rating : 852/5 ( reviews)

Mast Cells and Basophils - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mast Cells and Basophils write by Gianni Marone. This book was released on 2000-05-25. Mast Cells and Basophils available in PDF, EPUB and Kindle. Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.

Janeway's Immunobiology

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Release : 2010-06-22
Genre : Medical
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Book Rating : 575/5 ( reviews)

Janeway's Immunobiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Janeway's Immunobiology write by Kenneth Murphy. This book was released on 2010-06-22. Janeway's Immunobiology available in PDF, EPUB and Kindle. The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Inflammation and the Microcirculation

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Release : 2010
Genre : Medical
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Book Rating : 656/5 ( reviews)

Inflammation and the Microcirculation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Inflammation and the Microcirculation write by D. Neil Granger. This book was released on 2010. Inflammation and the Microcirculation available in PDF, EPUB and Kindle. The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References

The Impact of Food Bioactives on Health

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Release : 2015-04-29
Genre : Technology & Engineering
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Book Rating : 040/5 ( reviews)

The Impact of Food Bioactives on Health - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Impact of Food Bioactives on Health write by Kitty Verhoeckx. This book was released on 2015-04-29. The Impact of Food Bioactives on Health available in PDF, EPUB and Kindle. “Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.

Cell Biology and Immunology of Leukocyte Function

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Release : 1979
Genre : Nature
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Book Rating : /5 ( reviews)

Cell Biology and Immunology of Leukocyte Function - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cell Biology and Immunology of Leukocyte Function write by Michael R. Quastel. This book was released on 1979. Cell Biology and Immunology of Leukocyte Function available in PDF, EPUB and Kindle. Cell Biology and Immunology of Leukocyte Function is a collection of papers presented at the 12th International Leukocyte Culture Conference, held in Beersheba, Israel on June 1978. This book is organized into seven parts encompassing 111 chapters. The contributors cover the different aspects of cell biology and immunology and the unique leukocyte function. Part I describes the mechanism of lymphocyte activation, the structure and function of the plasma membrane, and the macromolecular synthesis during lymphocyte activation. This part also deals with the interaction of lymphocytes with mitogenic lectins, the comparison of the mitogenic and nonmitogenic lectin binding, and the role of macrophages in the response of lymphocytes to lectins. Part II explores the thymic factors and the development of characteristic markers, antigens, and receptors. This part particularly emphasizes lymphocyte differentiation. Parts III and IV examine the genetic control and intercellular interactions involved in leukocyte function and the parameters of the immune response under in vitro conditions. Chapters on cytotoxicity, the mechanisms of phagocytic killing, autoimmunity, and the responses of leukocytes to tumor cells are included in these parts. Part V discusses the interactions of viruses and leukocytes and provides data on the physical mapping and analysis of sarcoma and leukemia viruses, while Part VI considers the application of leukocyte culture to problems of clinical medicine. Part VII involves the study of radiation effects, with an emphasis on the application of total lymphoid irradiation to the induction of transplantation tolerance. This part also looks into the role of the DNA repair process. Cell biologists, immunologists, and biomedical scientists and researchers will greatly benefit from this book.