Long-term Potentiation

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Author :
Release : 2004
Genre : Medical
Kind :
Book Rating : 305/5 ( reviews)

Long-term Potentiation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Long-term Potentiation write by Tim V. P. Bliss. This book was released on 2004. Long-term Potentiation available in PDF, EPUB and Kindle. In the thirty years since its discovery by Terje Lomo and Tim Bliss, Long Term Potentiation (LTP) has become one of the most extensively studied topics in contemporary neuroscience. In LTP the strength of synapses between neurons is potentiated following brief but intense activation. LTP is thought to play a central role in learning and memory, though the exact nature of its role is less clear. In spite of years of research, there are many questions about LTP regarding its functional relevance that remain unanswered - for example, is it a model of memory formation, or is the actual neural mechanism used by the brain to store information?This volume presents a state of the art account of LTP. It begins with lively accounts, by the scientists most closely involved, of the discovery of LTP and of the experiments that established its basic properties and induction mechanisms. Later contributions contain reviews and new research that cover the range of molecular, cellular, physiological and behavioural approaches to the study of LTP. Provocative, accessible, and authoritative, this book makes it clear why LTP continues in equal measure to puzzle and beguile neuroscientists today.Advance praise for Long Term Potentiation: 'This book provides a definitive overview of the development of ideas about synaptic plasticity and about the wide range of current research in this fascinating field.' Colin Blakemore, University of OxfordReadership: Neuroscientists from postgraduate level upwards

Synaptic Plasticity in the Hippocampus

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Release : 2012-12-06
Genre : Medical
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Book Rating : 02X/5 ( reviews)

Synaptic Plasticity in the Hippocampus - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Synaptic Plasticity in the Hippocampus write by Helmut L. Haas. This book was released on 2012-12-06. Synaptic Plasticity in the Hippocampus available in PDF, EPUB and Kindle. This is the second time that I have had the honor of opening an interna tional symposium dedicated to the functions of the hippocampus here in Pecs. It was a pleasure to greet the participants in the hope that their valuable contributions will make this meeting a tradition in this town. As one of the hosts of the symposium, I had the sorrowful duty to remind you of the absence of a dear colleague, Professor Graham God dard. His tragic and untimely death represents the irreparable loss of both a friend and an excellent researcher. This symposium is dedicated to his memory. If I compare the topics of the lectures of this symposium with those of the previous one, a striking difference becomes apparent. A dominating tendency of the previous symposium was to attempt to define hippocam pal function or to offer data relevant to supporting or rejecting existing theoretical positions. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip pocampal phenomena at the most elementary level. Electrical, biochemi cal, biophysical, and pharmacological events at the synaptic, membrane, or intracellular level are analyzed without raising the question of what kind of integral functions these elementary phenomena are a part of.

Neuronal Mechanisms of Memory Formation

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Release : 2001
Genre : Medical
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Book Rating : 67X/5 ( reviews)

Neuronal Mechanisms of Memory Formation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neuronal Mechanisms of Memory Formation write by Christian Hölscher. This book was released on 2001. Neuronal Mechanisms of Memory Formation available in PDF, EPUB and Kindle. Long-term potentiation (LTP) is by far the most dominant model for neuronal changes that might encode memory. LTP is an elegant concept that meets many criteria set up by theoreticians long before the model's discovery, and it also fits anatomical data of learning-dependent synapse changes. Since the discovery of LTP, the question has remained about how closely LTP produced in vitro by artificial stimulation of neurons actually models putative learning-induced synaptic changes. A number of recent investigations have tried to correlate synaptic changes observed after learning with changes produced by artificial stimulation of neurons. These studies have failed to find a correlation between the two forms of synaptic plasticity. In this book, an international group of neurobiologists and psychologists discuss their latest ideas and data. The results of experiments using electrophysiological techniques in vitro are discussed and compared with the results of in vivo experiments. Learning experiments are also discussed. Theoretical models such as the Hebb theory of synaptic changes during learning are compared to different models that do not predict upregulation of synaptic transmission. A wide approach is taken, and research and models in different brain areas such as the neocortex and the basal brain are discussed.

Long-term Potentiation

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Author :
Release : 1991
Genre : Depression, Mental
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Book Rating : 702/5 ( reviews)

Long-term Potentiation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Long-term Potentiation write by M. Baudry. This book was released on 1991. Long-term Potentiation available in PDF, EPUB and Kindle. Following the successful format of the first volume on long-term potentiation--a leading candidate for the neuronal basis of learning and memory--Volume 2 brings together the most recent data and hypotheses by top neuroscientists regarding the mechanisms of this phenomenon and of long-term depression (LTD).Following the successful format of the first volume on long- term potentiation--a leading candidate for the neuronal basis of learning and memory--Volume 2 brings together the most recent data and hypotheses by top neuroscientists regarding the mechanisms of this phenomenon and of long-term depression (LTD). The book is divided into several sections covering different aspects of the field ranging from molecular mechanisms of plasticity to computational neurobiology. It revisits some of the major points covered in Volume 1, updating them in this fast-moving field. It also introduces several new issues that have arisen since then. Of the many possible new topics that could have been added, the editors have focused on retrograde messengers and the mechanisms and functions of LTP and LTD because they are the subject of much interest, research, and controversy. The section on retrograde messengers deals primarily with nitric oxide.

Physical Exercise for Human Health

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Release : 2020-04-27
Genre : Medical
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Book Rating : 924/5 ( reviews)

Physical Exercise for Human Health - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Physical Exercise for Human Health write by Junjie Xiao. This book was released on 2020-04-27. Physical Exercise for Human Health available in PDF, EPUB and Kindle. This book shares the latest findings on exercise and its benefits in preventing and ameliorating numerous diseases that are of worldwide concern. Addressing the role of exercise training as an effective method for the prevention and treatment of various disease, the book is divided into eleven parts: 1) An Overview of the Beneficial Effects of Exercise on Health and Performance, 2) The Physiological Responses to Exercise, 3) Exercise and Metabolic Diseases, 4) Exercise and Cardiovascular Diseases, 5) Exercise and Musculoskeletal Diseases, 6) Exercise and Neurological and Psychiatric Diseases, 7) Exercise and the Respiration System, 8) Exercise and Immunity, 9) Exercise and HIV/AIDS, 10) Exercise and Neuropsychiatric Disorders, and 11) Future Prospects. Given its scope, the book will be particularly useful for researchers and students in the fields of physical therapy, physiology, medicine, genetics and cell biology, as well as researchers and physicians with a range of medical specialties.