Lung Cancer Metastasis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Lung Cancer Metastasis write by Venkateshwar Keshamouni. This book was released on 2009-09-18. Lung Cancer Metastasis available in PDF, EPUB and Kindle. Lung cancer is the leading cause of cancer-related mortality. Metastatic lung cancer is responsible for more than ninety percent of lung cancer related deaths. However, relatively little progress has been made in understanding the process of lung cancer metastasis. The two main aims of this book are a) to introduce clinical aspects to basic scientists and basic molecular and cellular concepts to clinical investigators, in order to promote collaboration and foster much needed translational research; and b) to introduce new and emerging concepts and approaches in metastasis research to lung cancer research community at large. In this attempt, the book will cover a broad spectrum of subjects ranging from the current trends in the clinical management of the metastatic disease, to the systems biology approach for gaining insights into the mechanisms of metastasis. Some of the subjects covered will include: defining basic hallmarks of a metastatic cell, the concept of tumor stem cells, epithelial-mesenchymal transitions, evasion of immune-surveillance, tumor-stromal interactions, angiogenesis, molecular imaging and biomarker discovery.
Pulmonary Metastasis
Pulmonary Metastasis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pulmonary Metastasis write by Leonard Weiss. This book was released on 1978. Pulmonary Metastasis available in PDF, EPUB and Kindle.
Introduction to Cancer Metastasis
Introduction to Cancer Metastasis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Introduction to Cancer Metastasis write by Aamir Ahmad. This book was released on 2016-11-14. Introduction to Cancer Metastasis available in PDF, EPUB and Kindle. Introduction to Cancer Metastasis provides, in one place, an overview of organ-specific cancer metastasis and the most common sites of cancer metastasis. Through specific chapters on individual primary cancers, their metastasis, and chapters on common metastatic sites, this volume comprehensively informs readers about the broader knowledge base in cancer metastasis. The process of metastasis is particularly responsible for making cancer so lethal. This volume explores both metastasis from sites of origin and common metastatic sites, thus increasing understanding of both perspectives. Includes basic biology and translational approaches to organ-specific cancer sites Provides readers with information on emerging therapeutic targets for cancer metastasis Contains contributions from leading researchers around the globe
Diseases of the Chest, Breast, Heart and Vessels 2019-2022
Diseases of the Chest, Breast, Heart and Vessels 2019-2022 - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Diseases of the Chest, Breast, Heart and Vessels 2019-2022 write by Juerg Hodler. This book was released on 2019-02-19. Diseases of the Chest, Breast, Heart and Vessels 2019-2022 available in PDF, EPUB and Kindle. This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.
Central Nervous System Metastases in Lung Cancer Patients: From Prevention to Diagnosis and Treatment
Central Nervous System Metastases in Lung Cancer Patients: From Prevention to Diagnosis and Treatment - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Central Nervous System Metastases in Lung Cancer Patients: From Prevention to Diagnosis and Treatment write by Lizza E.L Hendriks. This book was released on 2019-01-21. Central Nervous System Metastases in Lung Cancer Patients: From Prevention to Diagnosis and Treatment available in PDF, EPUB and Kindle. Approximately 40% of lung cancer patients will develop central nervous system (CNS) metastases during the course of their disease. Most of these are brain metastases, but up to 10% will develop leptomeningeal metastases. Known risk factors for CNS metastases development are small cell lung cancer (SCLC), adenocarcinoma histology, epidermal growth factor receptor (EGFR) mutant or anaplastic lymphoma kinase (ALK) rearranged lung cancer, advanced nodal status, tumor stage and younger age. CNS metastases can have a negative impact on quality of life (QoL) and overall survival (OS). The proportion of lung cancer patients diagnosed with CNS metastases has increased over the years due to increased use of brain imaging as part of initial cancer staging, advances in imaging techniques and better systemic disease control. Post contrast gadolinium enhanced magnetic resonance imaging (gd-MRI) is preferred, however when this is contra-indicated a contrast enhanced computed tomography (CE-CT) is mentioned as an alternative option. When CNS metastases are diagnosed, local treatment options consist of radiotherapy (stereotactic or whole brain) and surgery. Local treatment can be complicated by symptomatic radiation necrosis for which no high level evidence based treatment exists. Moreover, differential diagnosis with metastasis progression is difficult. Systemic treatment options have expanded over the last years. Until recently, chemotherapy was the only treatment option with a poor penetration in the CNS. Angiogenesis inhibitors are promising in the treatment of primary CNS tumors as well as radiation necrosis but clinical trials of anti-angiogenic agents in NSCLC have largely excluded patients with CNS metastases. Furthermore, research has also focused on methods to prevent development of CNS disease, for example with prophylactic cranial irradiation. Recently, checkpoint inhibitors have become available for NSCLC patients, and tyrosine kinase inhibitors (TKIs) have improved prognosis significantly in those with a druggable driver mutation. Newer TKIs are often designed to have better CNS penetration compared to first-generation TKIs. Despite advances in treatment options CNS metastases remain a problem in lung cancer and cause morbidity and mortality. This Research Topic provides an extensive resource of articles describing advances in CNS metastases management in lung cancer patients, from prevention to diagnosis and treatment.
