Management of Breast Cancer in Older Women - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Management of Breast Cancer in Older Women write by Malcolm W. Reed. This book was released on 2010-01-18. Management of Breast Cancer in Older Women available in PDF, EPUB and Kindle. I was looking at Mrs T – all 45 kilos of her – with somewhat puzzled thoughts. I had prescribed her capecitabine at very prudent doses, in view of her 91-year-old kidneys and physiology. She had reduced my treatment even further, “because it was making her tired.” As a result, she was taking a grand total of 500 mg of capecitabine a day. Yet, her metastatic, ER/PR-negative, Her2-positive breast cancer was undoubtedly responding. Her pain was improving and her chest mass was shrinking, as were her lung metastases... What was the secret of that response? Were Mrs T’s kidneys eli- nating even less drug than predicted by her creatinine clearance? Was her sarcopenia altering drug distribution? Was she absorbing more drug than average? Or was her tumor exquisitely sensitive to fluoropyrimidines? “Physicians,” said Voltaire, “pour drugs they know little for diseases they know even less into patients they know no- ing about.” Medicine has made tremendous progress since the eighteenth century. Yet, there are fields where quite a lot remains to be learned. In developed countries, 25% of breast cancers occur in patients aged 75 years and older. Yet, these patients represent only 4% of the population of traditional clinical trials. That ought to let us wonder how relevant data acquired in patients in their 60s are to a nonagenarian. Fortunately, geriatric oncologists have been stepping up to the task and have gen- ated data to help us to treat such patients.
Management of Breast Cancer in Older Women
Management of Breast Cancer in Older Women - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Management of Breast Cancer in Older Women write by Malcolm W. R. Reed. This book was released on 2019. Management of Breast Cancer in Older Women available in PDF, EPUB and Kindle. This book offers evidence-based clinical knowledge of older patients suffering from breast cancer. It details the full armament of therapeutic options as well as the epidemiology of the disease and specific psychosocial considerations for elderly patients.
Adjuvant Therapy of Breast Cancer
Adjuvant Therapy of Breast Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Adjuvant Therapy of Breast Cancer write by I. Craig Henderson. This book was released on 2012-11-05. Adjuvant Therapy of Breast Cancer available in PDF, EPUB and Kindle. The results of randomized trials evaluating the use of early or adjuvant systemic treatment for patients with resectable breast cancer provide an eloquent rebuttal to those who would argue that we have made no progress in the treatment of cancer. Many of the tumors that we have been most successful in curing with chemotherapy and other newer forms of treatment are relatively uncommon. In contrast, breast cancer continues to be the single most common malignancy among women in the western world, is increasingly a cause of death throughout Asia and Third-World countries, and remains one of the most substantial causes of cancer mortality world wide. The use of mammography as a means of early detection has been shown to reduce breast cancer mortality by 25-35% among those popu lations in which it is utilized. The use of adjuvant systemic treatment in appropriate patients provides a similar (and additional) reduction in breast cancer mortality. Few subjects have been so systematically studied in the history of medicine, and it seems fair to conclude that the value to adjuvant systemic therapy in prolonging the lives of women with breast cancer is more firmly supported by empirical evidence than even the more conventional or primary treatments using various combinations ofsurgery and radiotherapy.
Principles and Practice of Geriatric Surgery
Principles and Practice of Geriatric Surgery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Principles and Practice of Geriatric Surgery write by Ronnie Ann Rosenthal. This book was released on 2011-07-12. Principles and Practice of Geriatric Surgery available in PDF, EPUB and Kindle. "In the preface to this impressive and well-produced book, the editors state that their aim is not to describe a new surgical specialty, since most surgeons will soon need to be "geriatric surgeons," but to assemble a comprehensive account that will allow "all providers of healthcare to the elderly to understand the issues involved in choosing surgery as a treatment option for their patients." This is a useful book that deserves to do well. I hope that the editors and their publisher will have the stamina to make this the first of several editions, as it is clear that updated information about surgery in the elderly will be required to keep pace with this important field." NEJM Book Review
Cancer in the Elderly
Cancer in the Elderly - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cancer in the Elderly write by Carrie P. Hunter. This book was released on 2000-03-01. Cancer in the Elderly available in PDF, EPUB and Kindle. This book presents comprehensive assessment and up-to-date discussion of the epidemiology, prevention, and treatment of cancer in the elderly, highlighting the growing demands of the disease, its biology, individual susceptibility, the impact of state-of-the-art and emerging therapies on reducing morbidity, and decision making processes. Describ
