Mass Spectrometry Data Analysis in Proteomics

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Author :
Release : 2013
Genre : Mass spectrometry
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Book Rating : 923/5 ( reviews)

Mass Spectrometry Data Analysis in Proteomics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mass Spectrometry Data Analysis in Proteomics write by Rune Matthiesen. This book was released on 2013. Mass Spectrometry Data Analysis in Proteomics available in PDF, EPUB and Kindle. Since the publishing of the first edition, the methodologies and instrumentation involved in the field of mass spectrometry-based proteomics has improved considerably. Fully revised and expanded, Mass Spectrometry Data Analysis in Proteomics, Second Edition presents expert chapters on specific MS-based methods or data analysis strategies in proteomics. The volume covers data analysis topics relevant for quantitative proteomics, post translational modification, HX-MS, glycomics, and data exchange standards, among other topics. Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Updated and authoritative, Mass Spectrometry Data Analysis in Proteomics, Second Edition serves as a detailed guide for all researchers seeking to further our knowledge in the field of proteomics.

Neuroproteomics

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Release : 2009-10-26
Genre : Medical
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Book Rating : 264/5 ( reviews)

Neuroproteomics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neuroproteomics write by Oscar Alzate. This book was released on 2009-10-26. Neuroproteomics available in PDF, EPUB and Kindle. In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Mass Spectrometry-Based Chemical Proteomics

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Release : 2019-07-10
Genre : Science
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Book Rating : 217/5 ( reviews)

Mass Spectrometry-Based Chemical Proteomics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mass Spectrometry-Based Chemical Proteomics write by W. Andy Tao. This book was released on 2019-07-10. Mass Spectrometry-Based Chemical Proteomics available in PDF, EPUB and Kindle. PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS—EMPHASIZING MASS SPECTROMETRY THROUGHOUT Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments. The first section of Mass Spectrometry-Based Chemical Proteomics starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures. Summarizes chemical proteomics, up-to-date concepts, analysis, and target validation Covers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions Explains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics Includes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products Addresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry Mass Spectrometry-Based Chemical Proteomics is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.

Activity-Based Protein Profiling

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Release : 2019-01-25
Genre : Medical
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Book Rating : 431/5 ( reviews)

Activity-Based Protein Profiling - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Activity-Based Protein Profiling write by Benjamin F. Cravatt. This book was released on 2019-01-25. Activity-Based Protein Profiling available in PDF, EPUB and Kindle. This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions.

Quantitative Proteomics by Mass Spectrometry

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Release : 2018-04-15
Genre : Science
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Book Rating : 666/5 ( reviews)

Quantitative Proteomics by Mass Spectrometry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Quantitative Proteomics by Mass Spectrometry write by Salvatore Sechi. This book was released on 2018-04-15. Quantitative Proteomics by Mass Spectrometry available in PDF, EPUB and Kindle. This volume describes prominent methodologies developed by laboratories that have been leading the field of quantitative proteomics by mass spectrometry. The procedures for performing the experiments are described in an easy-to-understand manner with many technical details that usually are not reported in typical research articles. This second edition of Quantitative Proteomics by Mass Spectrometry provides a broad perspective of the methodologies used for quantifying proteins and post-translational modifications in different types of biomedical specimens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Quantitative Proteomics by Mass Spectrometry, Second Edition is a valuable resource to help researchers understand and learn about the latest tools used in the study of quantitative proteomics by mass spectrometry.