Mass Spectrometry for the Clinical Laboratory

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Release : 2016-11-02
Genre : Science
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Book Rating : 926/5 ( reviews)

Mass Spectrometry for the Clinical Laboratory - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mass Spectrometry for the Clinical Laboratory write by Hari Nair. This book was released on 2016-11-02. Mass Spectrometry for the Clinical Laboratory available in PDF, EPUB and Kindle. Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab

Principles and Applications of Clinical Mass Spectrometry

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Release : 2018-06-26
Genre : Science
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Book Rating : 640/5 ( reviews)

Principles and Applications of Clinical Mass Spectrometry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Principles and Applications of Clinical Mass Spectrometry write by Nader Rifai. This book was released on 2018-06-26. Principles and Applications of Clinical Mass Spectrometry available in PDF, EPUB and Kindle. Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. Provides concrete examples of the main applications of mass spectrometry technology Describes current capabilities of the LC- and MS-based analytical methods Details methods for successful analytical work in the field

Mass spectrometry in the clinical laboratory : general principles and guidance ; approved guideline

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Release : 2007
Genre : Diagnosis, Laboratory
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Book Rating : 481/5 ( reviews)

Mass spectrometry in the clinical laboratory : general principles and guidance ; approved guideline - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mass spectrometry in the clinical laboratory : general principles and guidance ; approved guideline write by Donald H. Chace. This book was released on 2007. Mass spectrometry in the clinical laboratory : general principles and guidance ; approved guideline available in PDF, EPUB and Kindle.

Clinical Applications of Mass Spectrometry in Biomolecular Analysis

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Release : 2015-11-25
Genre : Medical
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Book Rating : 811/5 ( reviews)

Clinical Applications of Mass Spectrometry in Biomolecular Analysis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Clinical Applications of Mass Spectrometry in Biomolecular Analysis write by Uttam Garg. This book was released on 2015-11-25. Clinical Applications of Mass Spectrometry in Biomolecular Analysis available in PDF, EPUB and Kindle. This volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and no need for specialized reagents. The techniques described are a must for the measurement of many clinically relevant analytes in the fields of drug analysis, endocrinology, and inborn errors of metabolism. Each chapter provides a brief introduction about a specified analyte, followed by detailed instructions on the analytical protocol. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols is a great resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.

Mass Spectrometry, An Issue of Clinics in Laboratory Medicine

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Release : 2011-12-28
Genre : Medical
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Book Rating : 019/5 ( reviews)

Mass Spectrometry, An Issue of Clinics in Laboratory Medicine - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mass Spectrometry, An Issue of Clinics in Laboratory Medicine write by Nigel Clarke. This book was released on 2011-12-28. Mass Spectrometry, An Issue of Clinics in Laboratory Medicine available in PDF, EPUB and Kindle. This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; and Regulatory Considerations.