Mechanobiology

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Release : 2019-12-01
Genre : Science
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Book Rating : 325/5 ( reviews)

Mechanobiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mechanobiology write by Glen L. Niebur. This book was released on 2019-12-01. Mechanobiology available in PDF, EPUB and Kindle. Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli Provides a review of diseases with known or purported mechanobiological underpinnings Includes the role of mechanobiology in tissue engineering and regenerative medicine Covers experimental methods to capture mechanobiological phenomena

Mechanobiology in Health and Disease

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Release : 2018-08-09
Genre : Medical
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Book Rating : 530/5 ( reviews)

Mechanobiology in Health and Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mechanobiology in Health and Disease write by Stefaan Verbruggen. This book was released on 2018-08-09. Mechanobiology in Health and Disease available in PDF, EPUB and Kindle. Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science

Mechanobiology

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Release : 2017-02-06
Genre : Science
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Book Rating : 147/5 ( reviews)

Mechanobiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mechanobiology write by Simon C. F. Rawlinson. This book was released on 2017-02-06. Mechanobiology available in PDF, EPUB and Kindle. An emerging field at the interface of biology and engineering, mechanobiology explores the mechanisms by which cells sense and respond to mechanical signals—and holds great promise in one day unravelling the mysteries of cellular and extracellular matrix mechanics to cure a broad range of diseases. Mechanobiology: Exploitation for Medical Benefit presents a comprehensive overview of principles of mechanobiology, highlighting the extent to which biological tissues are exposed to the mechanical environment, demonstrating the importance of the mechanical environment in living systems, and critically reviewing the latest experimental procedures in this emerging field. Featuring contributions from several top experts in the field, chapters begin with an introduction to fundamental mechanobiological principles; and then proceed to explore the relationship of this extensive force in nature to tissues of musculoskeletal systems, heart and lung vasculature, the kidney glomerulus, and cutaneous tissues. Examples of some current experimental models are presented conveying relevant aspects of mechanobiology, highlighting emerging trends and promising avenues of research in the development of innovative therapies. Timely and important, Mechanobiology: Exploitation for Medical Benefit offers illuminating insights into an emerging field that has the potential to revolutionise our comprehension of appropriate cell biology and the future of biomedical research.

Mechanobiology of Cell-Cell and Cell-Matrix Interactions

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Release : 2011-02-21
Genre : Technology & Engineering
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Book Rating : 830/5 ( reviews)

Mechanobiology of Cell-Cell and Cell-Matrix Interactions - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mechanobiology of Cell-Cell and Cell-Matrix Interactions write by A. Wagoner Johnson. This book was released on 2011-02-21. Mechanobiology of Cell-Cell and Cell-Matrix Interactions available in PDF, EPUB and Kindle. Mechanobiology of Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediate cell behavior. Studies of cell-matrix interactions rely on integrating engineering, (molecular and cellular) biology, and imaging disciplines. Recent advances in the field have begun to unravel our understanding of how cells gather information from their surrounding environment, and how they interrogate such information during the cell fate decision making process. Topics include adhesive and integrin-ligand interactions; extracellular influences on cell biology and behavior; cooperative mechanisms of cell-cell and cell-matrix interactions; the mechanobiology of pathological processes; (multi-scale) modeling approaches to describe the complexity or cell-matrix interactions; and quantitative methods required for such experimental and modeling studies.

Mechanobiology

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Author :
Release : 2004
Genre : Medical
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Book Rating : 368/5 ( reviews)

Mechanobiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mechanobiology write by J. F. Stoltz. This book was released on 2004. Mechanobiology available in PDF, EPUB and Kindle. Mechanobiology is now a vigorous branch of biomechanics and biorheology which is mainly concerned with the study of the influence of mechanical forces on cells and tissues and their clinical or therapeutical applications. As we are now at the age of proteomics and genomics and of cell micromechanical approaches, using methods like laser tweezers or confocal microscopy, mechanobiology brings new challenges. With these new researches, mechanobiology is the promise of new diagnostic and therapeutic approaches. T to the system under scrutiny and that stresses are implicated in tissue physiology (for example by the production of the extracellular matrix), secretions (i.e. production of NO and prostaglandins by endothelial cells), or for the induction of specific functions via intercellular communication; hence the interest from pharmacology in studies on new molecules. Moreover, these new findings have led to the development of tissue engineering, which is the concept of substitute tissue developed in vitro, from bioresorbable or non-bioresorbable scaffolds and from cells harvested in a physiologic mechanical environment such as from cartilage, bone and vessels. At the same time, the problem of cell grafting in tissue repair and especially the use of stem cells have led to new therapeutic fields.