Material-based Mechanobiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Material-based Mechanobiology write by Jun Nakanishi. This book was released on 2022-08-12. Material-based Mechanobiology available in PDF, EPUB and Kindle. Mechanobiology is a new research field that investigates how the physical forces and changes in mechanical properties of cells and tissues contribute to their development, physiology and disease. One unique feature in the mechanical regulation, distinct from chemical/biochemical one, is that it can directly react with the multi-layered architectures of living systems, ranging from nano-scale proteins, subcellular organelles, cells, tissues, organs to whole bodies; one could term it “mechanoarchitectonics”. Another important aspect is its time-dependent dynamic feature. Not only time evolution in cells and extracellular matrices, but their intrinsic viscoelastic nature makes mechanical interaction dissipative and such feature is critical in cellular mechanical responses. This book focuses on recent progress in mechanobiology from the materials science perspective, encompassing innovative material designs for force measurements and actuation to resolve dynamic mechanobiology and mechanoarchitectonics, by better mimicking physiologically relevant and time-evolving cellular mechanical environments. It also shows the marriage between cutting-edge materials science which enable spatiotemporal manipulation of material and cell dynamics in multi-dimensions and molecular biological techniques such as genome editing and next generation sequencing for cell fate/motility engineering and disease modelling, with the aim of providing valuable insights into the latest technological advances and discoveries in areas such as stem cell, fibroblast, heart, tumour, and epithelial mechanobiology. Edited by leaders in the field, this book will be suitable for a broad range of readers, including materials scientists, biomaterial and biomedical engineering researchers and those working in chemical and mechanical engineering to expand possibilities of system designs for the developments of medical technologies based on mechanobiology.
Mechanobiology of Cell-Cell and Cell-Matrix Interactions
Mechanobiology of Cell-Cell and Cell-Matrix Interactions - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mechanobiology of Cell-Cell and Cell-Matrix Interactions write by A. Wagoner Johnson. This book was released on 2011-02-21. Mechanobiology of Cell-Cell and Cell-Matrix Interactions available in PDF, EPUB and Kindle. Mechanobiology of Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediate cell behavior. Studies of cell-matrix interactions rely on integrating engineering, (molecular and cellular) biology, and imaging disciplines. Recent advances in the field have begun to unravel our understanding of how cells gather information from their surrounding environment, and how they interrogate such information during the cell fate decision making process. Topics include adhesive and integrin-ligand interactions; extracellular influences on cell biology and behavior; cooperative mechanisms of cell-cell and cell-matrix interactions; the mechanobiology of pathological processes; (multi-scale) modeling approaches to describe the complexity or cell-matrix interactions; and quantitative methods required for such experimental and modeling studies.
Mechanobiology of Cells and Materials
Mechanobiology of Cells and Materials - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mechanobiology of Cells and Materials write by . This book was released on . Mechanobiology of Cells and Materials available in PDF, EPUB and Kindle.
Mechanobiology in Health and Disease
Mechanobiology in Health and Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mechanobiology in Health and Disease write by Stefaan Verbruggen. This book was released on 2018-08-09. Mechanobiology in Health and Disease available in PDF, EPUB and Kindle. Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science
Mechanobiology
Mechanobiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mechanobiology write by Ronen Zaidel-Bar. This book was released on 2023-01-01. Mechanobiology available in PDF, EPUB and Kindle. This detailed book collects methodologies exploring mechanobiology, the involvement of mechanical forces in cell fate specification and in controlling single and collective cell behaviors such as directed migration, morphogenesis, wound healing, and the immune response. The volume features methods to quantify the mechanical properties of cells and adhesion proteins, to expose cells to external mechanical forces, to quantitatively characterize mechano-responses at various scales, to measure forces applied by cells on the extracellular matrix, as well as chapters on force measurement inside cells, probing cell signaling and gene expression in response to force, and biophysical modeling of cell shape and protein dynamics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary material and reagents, step-by-step and readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Mechanobiology: Methods and Protocols aims to provide meaningful tools for cell and developmental biologists approaching the study of cell and tissue dynamics from a mechanobiological perspective, molecular biologists interested in the effects of force on proteins, as well as for cancer biologists and biophysicists.
