Metabolic Regulation and Metabolic Engineering for Biofuel and Biochemical Production

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Release : 2017-07-12
Genre : Science
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Book Rating : 385/5 ( reviews)

Metabolic Regulation and Metabolic Engineering for Biofuel and Biochemical Production - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Metabolic Regulation and Metabolic Engineering for Biofuel and Biochemical Production write by Kazuyuki Shimizu. This book was released on 2017-07-12. Metabolic Regulation and Metabolic Engineering for Biofuel and Biochemical Production available in PDF, EPUB and Kindle. The global warming problem is becoming critical year by year, causing climate disaster all over the world, where it has been believed that the CO2 gas emitted from the factories and the burning of fossil fuels may be one of the reasons of global warming. Moreover, the global stock of fossil fuels is limited, and may run out soon within several tens of years. Although wind, geo-thermal, and tide energies have been considered as clean energy sources, those depend on the land or sea locations and subject to the climate change. Biofuel and biochemical production from renewable bio-resources has thus been paid recent attention from environmental protection and energy production points of view, where the current chemical and energy producing plants can be also utilized with slight modification. The so-called 1st generation biofuels have been produced from corn starch and sugarcane in particular in USA and Brazil. However, this causes the problem of the so-called "food and energy issues" as the production scale increases. The 2nd generation biofuel production from lingo-cellulosic biomass or wastes has thus been paid recent attention. However, it requires energy intensive pretreatment for the degradation of lingo-cellulosic biomass, and the fermentation is slow due to low growth rate, and thus the productivity of biofuels and bio-chemicals is low. The 3rd generation biofuel production from photosynthetic organisms such as cyanobacteria and algae has been also paid attention, because such organisms can grow with only sun light and CO2 in the air, but the cell growth rate and thus the productivity of the fuels is significantly low. The main part or core of such production processes is the fermentation by micro-organisms. In particular, it is critical to properly understand the cell metabolism followed by the efficient metabolic engineering. The book gives comprehensive explanation of the cell metabolism and the metabolic regulation mechanisms of a variety of micro-organisms. Then the efficient metabolic engineering approaches are explained to properly design the microbial cell factories for the efficient cell growth and biofuel and biochemical production.

Metabolic Engineering

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Release : 2003-07-03
Genre : Science
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Book Rating : 008/5 ( reviews)

Metabolic Engineering - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Metabolic Engineering write by Jens Nielsen. This book was released on 2003-07-03. Metabolic Engineering available in PDF, EPUB and Kindle. Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.

Metabolic Engineering for Bioprocess Commercialization

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Release : 2016-07-16
Genre : Science
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Book Rating : 668/5 ( reviews)

Metabolic Engineering for Bioprocess Commercialization - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Metabolic Engineering for Bioprocess Commercialization write by Stephen Van Dien. This book was released on 2016-07-16. Metabolic Engineering for Bioprocess Commercialization available in PDF, EPUB and Kindle. This volume reviews the current metabolic engineering tools and technologies from a practical point of view, and guides researchers as they overcome challenges at various stages of organism and bioprocess development. Microbes have been engineered to produce a variety of industrial products such as fuels, basic chemicals, fine chemicals, nutritional supplements, and pharmaceutical intermediates, and new tools such as gene synthesis, advanced cloning techniques, ‘omics’ analysis, and mathematical modeling have greatly accelerated the pace of innovation in the field. Written by leading experts in the field from both academia and industry, key topics include synthetic biology, pathway engineering, metabolic flux manipulation, adaptive evolution, and fermentation process scale-up. It is suitable for non-specialists, and is a valuable resource for anyone embarking on the exciting path to harnessing the metabolic potential of microorganisms.

Metabolic Engineering

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Release : 2021-06-02
Genre : Science
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Book Rating : 45X/5 ( reviews)

Metabolic Engineering - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Metabolic Engineering write by Sang Yup Lee. This book was released on 2021-06-02. Metabolic Engineering available in PDF, EPUB and Kindle. Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.

Biotechnology for Biofuel Production and Optimization

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Release : 2016-01-19
Genre : Science
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Book Rating : 537/5 ( reviews)

Biotechnology for Biofuel Production and Optimization - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Biotechnology for Biofuel Production and Optimization write by Carrie A Eckert. This book was released on 2016-01-19. Biotechnology for Biofuel Production and Optimization available in PDF, EPUB and Kindle. Biotechnology for Biofuel Production and Optimization is the compilation of current research findings that cover the entire process of biofuels production from manipulation of genes and pathways to organisms and renewable feedstocks for efficient biofuel production as well as different cultivation techniques and process scale-up considerations. This book captures recent breakthroughs in the interdisciplinary areas of systems and synthetic biology, metabolic engineering, and bioprocess engineering for renewable, cleaner sources of energy. Describes state-of-the-art engineering of metabolic pathways for the production of a variety of fuel molecules Discusses recent advances in synthetic biology and metabolic engineering for rational design, construction, evaluation of novel pathways and cell chassis Covers genome engineering technologies to address complex biofuel-tolerant phenotypes for enhanced biofuel production in engineered chassis Presents the use of novel microorganisms and expanded substrate utilization strategies for production of targeted fuel molecules Explores biohybrid methods for harvesting bioenergy Discusses bioreactor design and optimization of scale-up