Microbial Transformations of Steroids

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Release : 2013-12-01
Genre : Science
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Book Rating : 035/5 ( reviews)

Microbial Transformations of Steroids - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Microbial Transformations of Steroids write by M. Capek. This book was released on 2013-12-01. Microbial Transformations of Steroids available in PDF, EPUB and Kindle. Fundamental studies of steroid compounds have begun approximately thirty years ago with the solution of structures of cholesterol and bile acids. This field has been receiving more attention when the structures of the principal steroid hormones, aglycones of heart glycosides, sapogenins, steroid alkaloids, toad poisons have been established. An intensive interest in these derivatives of cyc1opentanoperhydrophe nanthrene was determined especially by practical viewpoints, notably by attempts to prepare by synthetical economical procedures a series of steroid hormones and their biologically active derivatives, further by theoretical viewpoints. Biochemistry of steroids was developing in its beginnings by studies of meta bolites of steroid hormones in animal organism and soon has brought a number of practical results that could be used also in medical diagnostics. Considerably later, the metabolism of steroid compounds was followed also in microorganisms, again in connection with the practical problem to aid to economical syntheses of some steroid hormones. Two names are of primary importance for the pioneer works in microbial transformations of steroids, that of the Italian worker L. MAMOLI who first realized the microbial biosynthesis of testosterone from dehydroepiandro sterone, and of the American chemist and microbiologist D. H. PETERSON, who has contributed by his fundamental experiments in microbial hydroxylation of steroids to the position eleven, especially to the synthesis of cortisone. Microbial transforma tions of steroids nowadays offer a valuable tool in the preparation of series otherwise difficultly accessible steroid compounds.

Microbial Transformations of Steroids

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Release : 2014-06-28
Genre : Science
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Book Rating : 557/5 ( reviews)

Microbial Transformations of Steroids - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Microbial Transformations of Steroids write by William Charney. This book was released on 2014-06-28. Microbial Transformations of Steroids available in PDF, EPUB and Kindle. Microbial Transformations of Steroids: A Handbook aims to provide those who wish to use microbial transformations of steroids with a single source book starting from 1937 to the present. The handbook first offers information on the history of the microbial transformations of organic compounds, including earliest works on the study of nonsteroids and steroids; significance of discovery of anti-inflammatory action of cortisone; first hydroxylations and dehydrogenations; manufacture of natural and synthetic corticosteroids; and trends in research. The text then ponders on chemical classification of microbial transformations of steroids, as well as the role of enzymes in microbial transformations and the classes of reactions. The publication elaborates on the construction and use of the table. Topics include order of the table, nomenclature, description of the transformation leading to the product, yield, organism, and constants. The book also focuses on taxonomy and use of the table, including system of classification, specific notes on divisions of the table, and source of cultures. The handbook is a valuable source of data for readers interested in the microbial transformations of steroids.

Microbial Steroids

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Release : 2023-09-30
Genre : Science
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Book Rating : 856/5 ( reviews)

Microbial Steroids - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Microbial Steroids write by Carlos Barreiro. This book was released on 2023-09-30. Microbial Steroids available in PDF, EPUB and Kindle. This detailed volume explores experimental laboratory procedures for a wide range of steroid bioconversions. After an overview on the current trends and perspectives, the book continues with sections covering microbial screening and synthetic biology applied to microorganisms able to catabolize sterols, methods on strain characterization, including omics and biochemical analyses, methods of fermentation and biocatalysis for steroids production, as well as a chapter on the medical use of glucocorticoids in cancer patients. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microbial Steroids: Methods and Protocols, Second Edition serves as an ideal reference source for laboratory and industrial professionals, as well as for students in a wide array of biological disciplines.

Microbial Steroids

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Release : 2017-07-15
Genre : Science
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Book Rating : 824/5 ( reviews)

Microbial Steroids - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Microbial Steroids write by José-Luis Barredo. This book was released on 2017-07-15. Microbial Steroids available in PDF, EPUB and Kindle. This volume provides practical experimental laboratory protocols for a wide range of steroid bioconversions. The chapters in this book cover topics such as bioconversions and chemical synthesis pathways; strain characterization; bioconversion from sterols to androstenedione and androstadienedione; steroid hydroxylations; biocatalysis; and downstream processes to purify steroid intermediates. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and thorough, Microbial Steroids: Methods and Protocols is a valuable resource for laboratory and industrial professionals. It is also useful for graduate students studying biotechnology, microbiology, genetics, and molecular biology.

Steroid Microbiology

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Release : 1986
Genre : Medical
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Book Rating : /5 ( reviews)

Steroid Microbiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Steroid Microbiology write by Pinhas Margalith. This book was released on 1986. Steroid Microbiology available in PDF, EPUB and Kindle.