MicroRNAs in Diseases and Disorders - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook MicroRNAs in Diseases and Disorders write by Philip V Peplow. This book was released on 2019-05-07. MicroRNAs in Diseases and Disorders available in PDF, EPUB and Kindle. From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA mimics and inhibitors. With a global contribution list and chapters from leading experts across the field, MicroRNAs in Diseases and Disorders is an invaluable reference to miRNA researchers and health professionals in a variety of disease areas in government, academia and industry. The book will also appeal to pharmaceutical and medicinal chemists with an interest in miRNA targeting therapeutics, as well as to advanced students in chemical biology and drug discovery.
MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets
MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets write by Philip V Peplow. This book was released on 2019-05-21. MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets available in PDF, EPUB and Kindle. From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA mimics and inhibitors. With a global contribution list and chapters from leading experts across the field, MicroRNAs in Diseases and Disorders is an invaluable reference to miRNA researchers and health professionals in a variety of disease areas in government, academia and industry. The book will also appeal to pharmaceutical and medicinal chemists with an interest in miRNA targeting therapeutics, as well as to advanced students in chemical biology and drug discovery.
Hormones, Metabolism and the Benefits of Exercise
Hormones, Metabolism and the Benefits of Exercise - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Hormones, Metabolism and the Benefits of Exercise write by Bruce Spiegelman. This book was released on 2018-03-07. Hormones, Metabolism and the Benefits of Exercise available in PDF, EPUB and Kindle. The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Current Perspectives in microRNAs (miRNA)
Current Perspectives in microRNAs (miRNA) - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Current Perspectives in microRNAs (miRNA) write by Shao-Yao Ying. This book was released on 2008-09-12. Current Perspectives in microRNAs (miRNA) available in PDF, EPUB and Kindle. Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17–25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. Currently over 1000 native miRNA species found in vertebrates and many more new miRNA homologs continue to be identified; however, most of their functions remain to be determined. In this book, many new perspectives of the miRNA research are reviewed and discussed, including their roles in stem cell maintenance, embryonic development, tissue differentiation, adult physiology, disease pathology, cancer research, viral infection, genetic engineering in plants, and utility in cosmetic applications. These new findings may not only provide significant insight into the various mechanisms of miRNAs but also offer a great opportunity in developing new therapeutic interventions.
The Cystic Kidney
The Cystic Kidney - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Cystic Kidney write by K.D. Gardner. This book was released on 2012-12-06. The Cystic Kidney available in PDF, EPUB and Kindle. This is a book about renal cysts and cystic kidneys. Its contributors have created a resource of current information in a field that once aroused only curiosity, but that now stands at the leading edge of molecular nephrology. Its authorship includes 'oldtimers', who bring the wisdom of experience, and 'newcomers', whose presence attests to the contributions made by the investigative and technological advances of the past decade. Its text is organized to carry the reader from renal cyst to cystic renal disease. Each of its chapters defines or explores a challenge or an advance. Cells that line renal cysts are diverse in structure, type, and perhaps function. The cysts themselves lie within an interstitium that is not normal and may influence cyst development and growth. Experimental analogs of human disease offer increasing opportunities to basic researchers to examine, in sequence and under controlled circumstances, those events that favor nephron dilation, cyst growth and ultimate renal failure.
