Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles write by Huilin Ye. This book was released on 2020-01-02. Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles available in PDF, EPUB and Kindle. Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.
Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles
Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles write by Huilin Ye. This book was released on 2019. Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles available in PDF, EPUB and Kindle.
Multiscale Modeling of Particle Interactions
Multiscale Modeling of Particle Interactions - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Multiscale Modeling of Particle Interactions write by Michael King. This book was released on 2010-03-30. Multiscale Modeling of Particle Interactions available in PDF, EPUB and Kindle. Discover how the latest computational tools are building our understanding of particle interactions and leading to new applications With this book as their guide, readers will gain a new appreciation of the critical role that particle interactions play in advancing research and developing new applications in the biological sciences, chemical engineering, toxicology, medicine, and manufacturing technology The book explores particles ranging in size from cations to whole cells to tissues and processed materials. A focus on recreating complex, real-world dynamical systems helps readers gain a deeper understanding of cell and tissue mechanics, theoretical aspects of multiscale modeling, and the latest applications in biology and nanotechnology. Following an introductory chapter, Multiscale Modeling of Particle Interactions is divided into two parts: Part I, Applications in Nanotechnology, covers: Multiscale modeling of nanoscale aggregation phenomena: applications in semiconductor materials processing Multiscale modeling of rare events in self-assembled systems Continuum description of atomic sheets Coulombic dragging and mechanical propelling of molecules in nanofluidic systems Molecular dynamics modeling of nanodroplets and nanoparticles Modeling the interactions between compliant microcapsules and patterned surfaces Part II, Applications in Biology, covers: Coarse-grained and multiscale simulations of lipid bilayers Stochastic approach to biochemical kinetics In silico modeling of angiogenesis at multiple scales Large-scale simulation of blood flow in microvessels Molecular to multicellular deformation during adhesion of immune cells under flow Each article was contributed by one or more leading experts and pioneers in the field. All readers, from chemists and biologists to engineers and students, will gain new insights into how the latest tools in computational science can improve our understanding of particle interactions and support the development of novel applications across the broad spectrum of disciplines in biology and nanotechnology.
Multiscale Modeling of Particle Interactions
Multiscale Modeling of Particle Interactions - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Multiscale Modeling of Particle Interactions write by Michael King. This book was released on 2010-03-22. Multiscale Modeling of Particle Interactions available in PDF, EPUB and Kindle. Discover how the latest computational tools are building our understanding of particle interactions and leading to new applications With this book as their guide, readers will gain a new appreciation of the critical role that particle interactions play in advancing research and developing new applications in the biological sciences, chemical engineering, toxicology, medicine, and manufacturing technology The book explores particles ranging in size from cations to whole cells to tissues and processed materials. A focus on recreating complex, real-world dynamical systems helps readers gain a deeper understanding of cell and tissue mechanics, theoretical aspects of multiscale modeling, and the latest applications in biology and nanotechnology. Following an introductory chapter, Multiscale Modeling of Particle Interactions is divided into two parts: Part I, Applications in Nanotechnology, covers: Multiscale modeling of nanoscale aggregation phenomena: applications in semiconductor materials processing Multiscale modeling of rare events in self-assembled systems Continuum description of atomic sheets Coulombic dragging and mechanical propelling of molecules in nanofluidic systems Molecular dynamics modeling of nanodroplets and nanoparticles Modeling the interactions between compliant microcapsules and patterned surfaces Part II, Applications in Biology, covers: Coarse-grained and multiscale simulations of lipid bilayers Stochastic approach to biochemical kinetics In silico modeling of angiogenesis at multiple scales Large-scale simulation of blood flow in microvessels Molecular to multicellular deformation during adhesion of immune cells under flow Each article was contributed by one or more leading experts and pioneers in the field. All readers, from chemists and biologists to engineers and students, will gain new insights into how the latest tools in computational science can improve our understanding of particle interactions and support the development of novel applications across the broad spectrum of disciplines in biology and nanotechnology.
Multiscale Modeling of Dynamic Particle Systems
Multiscale Modeling of Dynamic Particle Systems - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Multiscale Modeling of Dynamic Particle Systems write by Brendon Waters. This book was released on 2021. Multiscale Modeling of Dynamic Particle Systems available in PDF, EPUB and Kindle. Modeling the dynamics of interacting many-particle systems is one of the central challenges at the forefront of condensed matter physics. When systems of interacting particles are driven out of equilibrium, complex emergent behaviors can arise that are difficult to predict from their individual properties. In this work, we model two such dynamic many-particle systems. The first is a nanocomposite of conductive CrO2and insulating Cr2O3 nanoparticles. We numerically model the nanoparticles as hard spherocylinders, systems of which are compressed into dense, disordered, packings via the mechanical contraction method, with various volume fractions of conductive CrO2. We then analyze the resulting ensembles of these nanocomposites to identify their critical percolation properties through a finite size scaling analysis. We use a randomly walking "blind ant" approach to calculate the conductivity of the nanocomposite and obtain the conductivity critical exponent of the nanocomposite system, which agrees with experimental measurements. Intriguingly, the calculated percolation threshold we obtained,pc= 0.312±0.002, is near (within numerical errors) those found previously in two other systems, disordered jammed spheres, and simple cubic lattice.The second type of system we model the evolution of is embedded grains in two dimensional (2D) crystals. We model 2D materials with the phase field crystal (PFC) model,which captures both atomic spatial resolution and slow diffusive dynamics, allowing for precise mapping of defect structures around evolving grain boundaries. We apply the Cahn-Taylor formulation of grain boundary motion to show that the normal motion of a shrinking embedded grain boundary couples to the tangential motion of atoms along the boundary,resulting in a net rotation of the grain as it changes size. Furthermore, we show that a more complex two component system such as hexagonal boron nitride (h-BN) exhibits a dual mode behavior of grain rotation, where the bonding energy difference between different atomic species results in competing rotations in opposite directions for binary embedded grains. This highlights the role played by the lattice inversion symmetry breaking in binary or multi-component materials as compared to single-component materials. The potential implications for processing techniques used to produce large crystals of 2D materials are also discussed.
