Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids write by Surendra Nimesh. This book was released on 2017-04-04. Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids available in PDF, EPUB and Kindle. Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field
Nanotechnology for the Delivery of Therapeutic Nucleic Acids
Nanotechnology for the Delivery of Therapeutic Nucleic Acids - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Nanotechnology for the Delivery of Therapeutic Nucleic Acids write by Dan Peer. This book was released on 2013-03-27. Nanotechnology for the Delivery of Therapeutic Nucleic Acids available in PDF, EPUB and Kindle. Nucleic acid (NA) therapeutics has been extensively studied both in the academia and in the pharmaceutical industry and is still considered the promise for new therapeutic modalities, especially in personalized medicine. The only hurdle that limits the translation of NA therapeutics from an academic idea to the new therapeutic modality is the lack
Nucleic Acids as Gene Anticancer Drug Delivery Therapy
Nucleic Acids as Gene Anticancer Drug Delivery Therapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Nucleic Acids as Gene Anticancer Drug Delivery Therapy write by Loutfy H. Madkour. This book was released on 2019-08-27. Nucleic Acids as Gene Anticancer Drug Delivery Therapy available in PDF, EPUB and Kindle. Nucleic Acids as Gene Anticancer Drug Delivery Therapy highlights the most recent developments in cancer treatment using nucleic acids, nanoparticles and polymer nanoparticles for genomic nanocarriers as drug delivery, including promising opportunities for targeted and combination therapy. The development of a wide spectrum of nanoscale technologies is beginning to change the scientific landscape in terms of disease diagnosis, treatment, and prevention. This book presents the use of nanotechnology for medical applications, focusing on its use for anticancer drug delivery. Various intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery are discussed. The use of smart drug delivery systems seems to be a promising approach for developing intelligent therapeutic systems for cancer immunotherapies and is discussed in detail along with nucleic acid-targeted drug delivery combination therapy for cancer. Nucleic Acids as Gene Anticancer Drug Delivery Therapy will be a useful reference for pharmaceutical scientists, pharmacologiests, and those involved in nanotechnology and cancer research. Discusses intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery Contains a comprehensive comparison of various delivery systems, listing their advantages and limitations Presents combination therapy as a new hope for enhancing current gene-based treatment efficacy
Therapeutic Oligonucleotides
Therapeutic Oligonucleotides - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Therapeutic Oligonucleotides write by Jens Kurreck. This book was released on 2008. Therapeutic Oligonucleotides available in PDF, EPUB and Kindle. This book provides a compelling overall update on current status of RNA interference
Nanotechnology for the Delivery of Therapeutic Nucleic Acids
Nanotechnology for the Delivery of Therapeutic Nucleic Acids - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Nanotechnology for the Delivery of Therapeutic Nucleic Acids write by Dan Peer. This book was released on 2013-03-27. Nanotechnology for the Delivery of Therapeutic Nucleic Acids available in PDF, EPUB and Kindle. Nucleic acid (NA) therapeutics has been extensively studied both in the academia and in the pharmaceutical industry and is still considered the promise for new therapeutic modalities, especially in personalized medicine. The only hurdle that limits the translation of NA therapeutics from an academic idea to the new therapeutic modality is the lack of efficient and safe delivery strategies. Nanotechnology for the Delivery of Therapeutic Nucleic Acids, written by world experts in the field of nanotechnology for NA delivery, the contributing authors bring together the state of the art in delivery strategies with strong emphasis on aspects that are of essence to the pharmaceutical industry, such as stability, general toxicity, immune-toxicity, pharmacokinetics, efficacy, and validation of new drug targets using unique approaches based on exquisite nanotechnology strategies.
