Negative Affective States and Cognitive Impairments in Nicotine Dependence

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Release : 2016-08-17
Genre : Psychology
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Book Rating : 693/5 ( reviews)

Negative Affective States and Cognitive Impairments in Nicotine Dependence - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Negative Affective States and Cognitive Impairments in Nicotine Dependence write by F. Scott Hall. This book was released on 2016-08-17. Negative Affective States and Cognitive Impairments in Nicotine Dependence available in PDF, EPUB and Kindle. Negative Affective States and Cognitive Impairments in Nicotine Dependence is the only book of its kind that addresses nicotine use and abuse in the context of negative reinforcement mechanisms. Written and edited by leading investigators in addiction, affective, genetic, and cognitive research, it provides researchers and advanced students with an overview of the clinical bases of these effects, allowing them to fully understand the various underlying dysfunctions that drive nicotine use in different individuals. In addition, this book examines animal models that researchers have utilized to investigate the biological bases of these dysfunctions. The combination of clinical and preclinical approaches to understanding nicotine dependence makes this book an invaluable resource for researchers and practitioners seeking to develop targeted treatments aimed at ameliorating symptoms of nicotine dependence, as well as identifying premorbid differences in affective or cognitive function. Provides a unique perspective on nicotine dependence that emphasizes negative reinforcement rather than positive reinforcement Examines psychiatric comorbidities and alleviation of withdrawal states as motivation for continued tobacco use Includes both clinical and preclinical perspectives Includes genetic and multi-neurotransmitter perspectives on nicotine use and withdrawal Emphasizes heterogeneity of underlying reasons for smoking, the need for multiple animal models to understand this heterogeneity, and the expectation of heterogeneous responses to potential treatments, underscoring the need for personalized therapeutics

Drugs, Addiction, and the Brain

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Release : 2014-07-12
Genre : Medical
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Book Rating : 595/5 ( reviews)

Drugs, Addiction, and the Brain - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Drugs, Addiction, and the Brain write by George F. Koob. This book was released on 2014-07-12. Drugs, Addiction, and the Brain available in PDF, EPUB and Kindle. Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction

Anhedonia: Preclinical, Translational, and Clinical Integration

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Release : 2022-08-08
Genre : Medical
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Book Rating : 835/5 ( reviews)

Anhedonia: Preclinical, Translational, and Clinical Integration - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Anhedonia: Preclinical, Translational, and Clinical Integration write by Diego A. Pizzagalli. This book was released on 2022-08-08. Anhedonia: Preclinical, Translational, and Clinical Integration available in PDF, EPUB and Kindle. Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson's Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that "anhedonia" can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to distinct neurobiological substrates that could underlie anhedonic phenotypes. Taking an integrative approach that emphasizes cross-species integration and dimensional conceptualization of mental illnesses (e.g., Research Domain Criteria (RDoC)), this book represents the most comprehensive evaluation, synthesis and integration of theories and empirical findings focused on anhedonia. Organized across five parts, the handbook starts with chapters on the history, etiology, and assessments of anhedonia (Part I), followed by a section on the role of anhedonia in psychiatric and neurological disorders (Part II). Using the RDoC Matrix as a guide, Part III presents chapters synthetizing preclinical and clinical findings on different reward processing subdomains (e.g., reward responsiveness, reward valuation, reward learning). Part IV is focused on selected special topics, including historical and current perspectives on the transdiagnostic nature and importance of social anhedonia, the role of inflammation in the pathophysiology of anhedonia, the use of computational modeling to “dissect” anhedonia and improve its understanding, and links between anhedonia and suicide. Finally, Part V includes chapters on pharmacological, psychological and neurostimulation treatments for anhedonia.

Brain and Cognition for Addiction Medicine: From Prevention to Recovery

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Release : 2021-01-12
Genre : Science
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Book Rating : 779/5 ( reviews)

Brain and Cognition for Addiction Medicine: From Prevention to Recovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Brain and Cognition for Addiction Medicine: From Prevention to Recovery write by Hamed Ekhtiari. This book was released on 2021-01-12. Brain and Cognition for Addiction Medicine: From Prevention to Recovery available in PDF, EPUB and Kindle.

Sleep and Health

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Release : 2019-04-17
Genre : Science
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Book Rating : 741/5 ( reviews)

Sleep and Health - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Sleep and Health write by Michael Grandner. This book was released on 2019-04-17. Sleep and Health available in PDF, EPUB and Kindle. Sleep and Health provides an accessible yet comprehensive overview of the relationship between sleep and health at the individual, community and population levels, as well as a discussion of the implications for public health, public policy and interventions. Based on a firm foundation in many areas of sleep health research, this text further provides introductions to each sub-area of the field and a summary of the current research for each area. This book serves as a resource for those interested in learning about the growing field of sleep health research, including sections on social determinants, cardiovascular disease, cognitive functioning, health behavior theory, smoking, and more. Highlights the important role of sleep across a wide range of topic areas Addresses important topics such as sleep disparities, sleep and cardiometabolic disease risk, real-world effects of sleep deprivation, and public policy implications of poor sleep Contains accessible reviews that point to relevant literature in often-overlooked areas, serving as a helpful guide to all relevant information on this broad topic area