Network Pharmacology and Traditional Medicine: Setting the New Standards by Combining In silico and Experimental Work - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Network Pharmacology and Traditional Medicine: Setting the New Standards by Combining In silico and Experimental Work write by Shao Li. This book was released on 2022-11-24. Network Pharmacology and Traditional Medicine: Setting the New Standards by Combining In silico and Experimental Work available in PDF, EPUB and Kindle.
Network Pharmacology
Network Pharmacology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Network Pharmacology write by Shao Li. This book was released on 2021-09-29. Network Pharmacology available in PDF, EPUB and Kindle. This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
Network Pharmacology and Traditional Medicine
Network Pharmacology and Traditional Medicine - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Network Pharmacology and Traditional Medicine write by Shao Li. This book was released on 2020. Network Pharmacology and Traditional Medicine available in PDF, EPUB and Kindle. This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Drug Discovery and Evaluation: Methods in Clinical Pharmacology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Drug Discovery and Evaluation: Methods in Clinical Pharmacology write by H.Gerhard Vogel. This book was released on 2010-12-15. Drug Discovery and Evaluation: Methods in Clinical Pharmacology available in PDF, EPUB and Kindle. Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Innovative Approaches in Drug Discovery
Innovative Approaches in Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Innovative Approaches in Drug Discovery write by Bhushan Patwardhan. This book was released on 2016-10-03. Innovative Approaches in Drug Discovery available in PDF, EPUB and Kindle. Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevant tools and technologies, the need is great and the time is now for a renewed commitment towards expanding the repertoire of medicines. By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences. Analyzes the reasons behind historical drug failures to provide valuable insights on lessons learned Uses current scientific research to promote learning from traditional knowledge systems and through the integration of traditional and western medicines Discusses advances in technologies and systems biology to support the transition from formulation discovery to therapeutic discovery
