Neural Regulation of Metabolism - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neural Regulation of Metabolism write by Qi Wu. This book was released on 2018-11-02. Neural Regulation of Metabolism available in PDF, EPUB and Kindle. This book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summarizes the humoral mechanisms by which critical adipocyte-derived hormones and lipoprotein lipase regulate lipid and glucose metabolism, and examines the role of the hypothalamus-sympathetic nerve, a critical nerve pathway from CNS to peripheral nervous system (PNS), in the regulation of metabolism in multiple tissues/organs. Furthermore, the book discusses the functions of adipose tissue in energy metabolism. Lastly, it explores dietary interventions to treat neural diseases and some of the emerging technologies used to study the neural regulation of metabolism. Presenting cutting-edge developments in the neural regulation of metabolism, the book is a valuable reference resource for graduate students and researchers in the field of neuroscience and metabolism.
Neuron Signaling in Metabolic Regulation
Neuron Signaling in Metabolic Regulation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neuron Signaling in Metabolic Regulation write by Qingchun Tong. This book was released on 2021-06-07. Neuron Signaling in Metabolic Regulation available in PDF, EPUB and Kindle. This book focuses on neuron signaling in the regulation of metabolism and body weight, and especially on methods used in these studies. Obesity and related metabolic syndromes have reached epidemic status, but still are no effective strategies for prevention and treatment. Body weight homeostasis is maintained by balanced food intake and energy expenditure, both of which are under the control of brain neurons. In the recent years, significant progress has been made in identifying specific neurons, neural pathways, and non-neuron cells in feeding regulation, as well as in delineating autonomic nervous systems targeting peripheral metabolic tissues in the regulation of energy expenditure and metabolism. This book reviews recent progress on important neuron signaling for body weight and metabolic regulation and the state-of-the-art methods that has been applied in this field, ranging from animal models with neuron-specific manipulations, pharmacology, optogenetics, in vivo Ca2+ imaging, and viral tracing. Readers will be exposed to latest research frontiers on neuron regulation of metabolism. Key Features Explores the role signaling between neurons plays with respect to metabolism Documents how neurotransmitters affect the regulation of feeding Describes various methods and technologies used to study the neuronal control of metabolism Includes contributions from an international team of leading researchers. Related Titles Lim, W. & B. Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Feltz, A. Physiology of Neurons (ISBN 978-0-8153-4600-5) Zempleni, J. & K. Dakshinamurti, eds. Nutrients and Cell Signaling (ISBN 978-0367-39307-6)
Neural Metabolism In Vivo
Neural Metabolism In Vivo - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neural Metabolism In Vivo write by In-Young Choi. This book was released on 2012-03-08. Neural Metabolism In Vivo available in PDF, EPUB and Kindle. From the preface: “Neural Metabolism In Vivo aims to provide a comprehensive overview of neurobiology by presenting the basic principles of up-to-date and cutting-edge technology, as well as their application in assessing the functional, morphological and metabolic aspects of the brain. Investigation of neural activity of the living brain via neurovascular coupling using multimodal imaging techniques extended our understanding of fundamental neurophysiological mechanisms, regulation of cerebral blood flow in connection to neural activity and the interplay between neurons, astrocytes and blood vessels. Constant delivery of glucose and oxygen for energy metabolism is vital for brain function, and the physiological basis of neural activity can be assessed through measurements of cerebral blood flow and consumption of glucose and oxygen.... This book presents the complex physiological and neurochemical processes of neural metabolism and function in response to various physiological conditions and pharmacological stimulations. Neurochemical detection technologies and quantitative aspects of monitoring cerebral energy substrates and other metabolites in the living brain are described under the “Cerebral metabolism of antioxidants, osmolytes and others in vivo” section. Altogether, the advent of new in vivo tools has transformed neuroscience and neurobiology research, and demands interdisciplinary approaches as each technology could only approximate a very small fraction of the true complexity of the underlying biological processes. However, translational values of the emerging in vivo methods to the application of preclinical to clinical studies cannot be emphasized enough. Thus, it is our hope that advances in our understanding of biochemical, molecular, functional and physiological processes of the brain could eventually help people with neurological problems, which are still dominated by the unknowns.” -- In-Young Choi and Rolf Gruetter
Neural Control of Hepatic Lipid Metabolism
Neural Control of Hepatic Lipid Metabolism - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neural Control of Hepatic Lipid Metabolism write by . This book was released on 2013. Neural Control of Hepatic Lipid Metabolism available in PDF, EPUB and Kindle. "Our body is well designed to store energy in times of nutrient excess and release energy in times of need. This adaptation to the external environment is achieved by both humoral factors and the autonomic nervous system. Already in the 19th century, Claude Bernard pointed out the importance of the autonomic nervous system in the control of glucose metabolism. In the next century, the discovery of insulin and the development of techniques to measure hormone concentrations shifted the focus of the control of metabolism to the secretion of hormones, thus functionally "decapitating" the body. Just before the end of the 20th century, starting with the discovery of leptin in 1994, the control of energy metabolism went back to our heads. Today, the autonomic nervous system is acknowledged as one of the important determinants of liver metabolism and as a possible treatment target. This thesis investigates the role of the autonomic nervous system in the control of hepatic lipid metabolism during different physiological conditions. We found that the sympathetic and parasympathetic nervous system represent complimentary forces, fine-tuning hepatic lipid metabolism during different nutritional states."--Samenvatting auteur.
Metabolism of the Nervous System
Metabolism of the Nervous System - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Metabolism of the Nervous System write by Derek Richter. This book was released on 2013-10-22. Metabolism of the Nervous System available in PDF, EPUB and Kindle. Metabolism of the Nervous System contains the proceedings of the 2nd International Neurochemical Symposium, held at Aarhus, Denmark, in July 1956. The book discusses the molecular structure and morphology of the adult nervous tissue; the chemical composition and cytochemical localization of adult nervous tissue; and the permeability and blood-brain barrier. The text also describes topics on electrolytes and nervous conduction; the metabolism of isolated nerve and ganglion; and the metabolism of the brain in vivo. The metabolism of brain tissue preparations in vitro; energy metabolism and coenzymes in relation to the nervous system; and lipid and fatty acid metabolism are also considered. The book further tackles nucleic acid metabolism; protein and amino acid metabolism; and cholinergic and non-cholinergic transmission. The text also discusses other pharmacologically active compounds related to the adult nervous tissue.
