Behavioral and Neural Genetics of Zebrafish

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Release : 2020-04-03
Genre : Medical
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Book Rating : 29X/5 ( reviews)

Behavioral and Neural Genetics of Zebrafish - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Behavioral and Neural Genetics of Zebrafish write by Robert T. Gerlai. This book was released on 2020-04-03. Behavioral and Neural Genetics of Zebrafish available in PDF, EPUB and Kindle. Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions. Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field Describes behavioral, genetic and neural methods and concepts for use in adult and larval zebrafish Features examples of zebrafish models of human central nervous system disorders Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics

Neuroethology of the Zebrafish

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Release : 2008
Genre : Animal behavior
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Book Rating : 793/5 ( reviews)

Neuroethology of the Zebrafish - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neuroethology of the Zebrafish write by Adam Raymond Kampff. This book was released on 2008. Neuroethology of the Zebrafish available in PDF, EPUB and Kindle. The complexity of the animal brain begs for simple tools that will assist scientists attempting to unravel the beautifully entangled mess. I begin by describing an experimental strategy for indentifying the components of neural circuits that control innate behaviors. My approach emphasizes the role of behavior analysis and the insights offered by neuroethology. While describing the neuroethological strategy, I will introduce the larval zebrafish and tools that I have developed to study the neural basis of innate visual behavior. The second chapter reports an implementation of the strategy that successfully revealed components of the circuit underlying the zebrafish optomotor reflex. We discovered distinct subsets of spinal projection neurons that were responsible for directing the swims and turns that constitute an important visual response to whole-field motion. The success of this study relied on the ability to record behavior-related neural activity in a restrained zebrafish, but this was found to be difficult for other visual behaviors. The third chapter addresses this problem by describing a novel technique to monitor neural activity in an unrestrained, behaving zebrafish. Employing the bioluminescent calcium reporter, Aequorin, we were able to detect the activity of Hypocretin neurons in freely swimming zebrafish. The success of this technique will allow an extensive survey of how identified populations of neurons collectively choreograph the complex behavior patterns of a developing vertebrate.

The world according to zebrafish: How neural circuits generate behaviour

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Release : 2014-11-07
Genre : Neurosciences. Biological psychiatry. Neuropsychiatry
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Book Rating : 284/5 ( reviews)

The world according to zebrafish: How neural circuits generate behaviour - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The world according to zebrafish: How neural circuits generate behaviour write by Gonzalo G. De Polavieja. This book was released on 2014-11-07. The world according to zebrafish: How neural circuits generate behaviour available in PDF, EPUB and Kindle. Understanding how the brain functions is one of the most ambitious current scientific goals. This challenge will only be accomplish by a multidisciplinary approach involving genetics, molecular biology, optics, ethology, neurobiology and mathematics and using tractable model systems. The zebrafish larva is a transparent genetically tractable small vertebrate, ideal for the combination state-of-the- art imaging techniques (e.g. two-photon scanning microscopy, single-plane illumination microscopy, spatial light modulator microscopy and lightfield microscopy), bioluminiscence and optogenetics to monitor and manipulate neuronal activity from single specific neurons up to the entire brain, in an intact behaving organism. Furthermore, the zebrafish model offers large and increasing collection of mutant and transgenic lines modelling human brain diseases. With these advantages in hand, the zebrafish larva became in the recent years, a novel animal model to study neuronal circuits and behaviour, taking us closer than ever before to understand how the brain controls behaviour.

Zebrafish Neurobehavioral Protocols

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Release : 2011-04-06
Genre : Medical
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Book Rating : 543/5 ( reviews)

Zebrafish Neurobehavioral Protocols - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Zebrafish Neurobehavioral Protocols write by Allan V. Kalueff. This book was released on 2011-04-06. Zebrafish Neurobehavioral Protocols available in PDF, EPUB and Kindle. As a model organism, zebrafish (Danio rerio) offer an opportunity to perform steadfast scientific investigations in a robust and high-throughput manner. In Zebrafish Neurobehavioral Protocols, experts in the field provide a series of detailed behavioral protocols dealing with the major current research areas in the field of behavioral neuroscience. The chapters discuss the use and interpretation of video-aided quantification of zebrafish behaviors, describe novel assays commonly used to quantify emotionality, learning, memory, and social behaviors in zebrafish, and instruct how to quantify endocrine responses and correlate them with behavior. Written in the Neuromethods series format, the chapters provide authoritative reviews of many commonly used approaches in the field today. This "how to" book will be a useful practical guide for zebrafish researchers and will complement another related book from this series, Zebrafish Models in Neurobehavioral Research. Cutting-edge and timely, Zebrafish Neurobehavioral Protocols serves as an excellent compilation epitomizing the growing potential of zebrafish in modern scientific inquiry.

Zebrafish Models in Neurobehavioral Research

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Release : 2016-08-23
Genre : Medical
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Book Rating : 228/5 ( reviews)

Zebrafish Models in Neurobehavioral Research - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Zebrafish Models in Neurobehavioral Research write by Allan V. Kalueff. This book was released on 2016-08-23. Zebrafish Models in Neurobehavioral Research available in PDF, EPUB and Kindle. Animal models have traditionally played a crucial role in improving our understanding of brain pathogenesis. Zebrafish (Danio rerio) have generated considerable discoveries in the areas of genetics, embryology, endocrinology, and neuroscience. Zebrafish Models in Neurobehavioral Research emphasizes the growing importance of zebrafish in neurobehavioral research and portrays an extensive, thorough perspective on the emergence of zebrafish as robust and translational models. Written by leading international experts, the book covers major topics ranging from stress to learned recognition of environment, encompassing a wide spectrum of the utility of zebrafish within neurobiological disciplines. The chapters provide authoritative reviews of many zebrafish paradigms commonly used in the field today. This book will be a useful guide for zebrafish researchers, and will complement another related book from the popular Neuromethods series, Zebrafish Neurobehavioral Protocols. Comprehensive and up-to-date, Zebrafish Models in Neurobehavioral Research serves as an ideal resource for scientists new to the field as well as for established researchers seeking valuable insight into the growing utility of zebrafish in neuroscience.