Neuroprogression and Staging in Bipolar Disorder - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neuroprogression and Staging in Bipolar Disorder write by Flávio Kapczinski. This book was released on 2015-06-11. Neuroprogression and Staging in Bipolar Disorder available in PDF, EPUB and Kindle. After the original proposals of staging for psychotic disorders developed by McGorry and colleagues, a few systems have been put forward specifically for people with bipolar disorder. There is now consistent evidence that, at least for a significant portion of people with this disease, clinical course and outcome are not as benign as initially described. The evidence thus far points to relevant differences between early and late stages of bipolar disorders in the clinical course of illness, neurobiology and systemic pathology. These differences all suggest that staging is a viable addition to clinical care in bipolar disorder. Neuroprogression and Staging in Bipolar Disorder provides a comprehensive summary of the current state of the evidence regarding the use of staging systems in bipolar disorder. Edited by the leading researchers in the field, the book systematically covers the theoretical basis for staging, comparisons between different proposals, neurobiological underpinnings, the current evidence-base, limitations and future directions, and clinical implications and recommendations for practice. The book provides a solid and in-depth outline and thus to influence research and practice in the field of bipolar disorder.
Neuroprogression in Psychiatry
Neuroprogression in Psychiatry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neuroprogression in Psychiatry write by Flávio Kapczinski. This book was released on 2019-03-05. Neuroprogression in Psychiatry available in PDF, EPUB and Kindle. Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found in patients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression. Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder.
Bipolar Disorder Vulnerability
Bipolar Disorder Vulnerability - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Bipolar Disorder Vulnerability write by Jair Soares. This book was released on 2018-06-12. Bipolar Disorder Vulnerability available in PDF, EPUB and Kindle. Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.
Neuroprogression and Staging in Bipolar Disorder
Neuroprogression and Staging in Bipolar Disorder - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neuroprogression and Staging in Bipolar Disorder write by Flávio Kapczinski. This book was released on 2015. Neuroprogression and Staging in Bipolar Disorder available in PDF, EPUB and Kindle. Neuroprogression and Staging in Bipolar Disorder provides a comprehensive and scholarly overview of clinical staging systems in the management of bipolar disorder. The book covers the theoretical basis, the neurobiological underpinnings, the current evidence base, limitations, future directions and the clinical implications and recommendations.
Neuroprogression in Psychiatric Disorders
Neuroprogression in Psychiatric Disorders - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neuroprogression in Psychiatric Disorders write by A. Halaris. This book was released on 2017-07-25. Neuroprogression in Psychiatric Disorders available in PDF, EPUB and Kindle. In this volume, international experts critically review cutting-edge advances in neuroprogression research. The relevance of these findings to psychiatric and neurological disorders is clarified. Potential etiopathological mechanisms of neuroprogression are described in detail. Special emphasis is placed on the role of the immune system in stress and stress-related disorders and brain-immune interactions. The epigenetic consequences of adverse experiences in early childhood, which may prelude major psychiatric disorders, are also considered. Recent research has not only provided evidence of neuroprogression in psychiatric and neurological disorders, but has shown that pharmacologic interventions have the potential to arrest this process. Advances in testing and imaging will lead to timely diagnosis and earlier treatment. Identification of neurological mechanisms alongside (epi-)genetic vulnerability markers will create truly personalized treatment programs. This book is a valuable resource for everyone who wishes to gain insight into the essential features of the neuroprogressive course of major psychiatric and neurological disorders. In particular, psychiatrists, neuroscientists and neurologists ¬ as well as immunologists, pharmacologists and molecular biologists - will find very informative chapters of direct relevance to their field.
