Neurotoxicology in Vitro

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Release : 1999-05-27
Genre : Medical
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Book Rating : 882/5 ( reviews)

Neurotoxicology in Vitro - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neurotoxicology in Vitro write by V. Pentreath. This book was released on 1999-05-27. Neurotoxicology in Vitro available in PDF, EPUB and Kindle. Written by a distinguished panel of experts, students and researchers will find that this comprehensive and accessible volume provides a framework for the study of nerve cells ^in vitro^n for use in experimental neurotoxicology.

In Vitro Neurotoxicology

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Release : 2008-02-06
Genre : Medical
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Book Rating : 517/5 ( reviews)

In Vitro Neurotoxicology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook In Vitro Neurotoxicology write by Evelyn Tiffany-Castiglioni. This book was released on 2008-02-06. In Vitro Neurotoxicology available in PDF, EPUB and Kindle. Well-respected leaders in the field of in vitro neurotoxicology take a fresh look at their own and other's work, critically and comparatively analyzing it across experimental systems and toxicants, and synthesizing essential principles for in vitro neurotoxicity testing. Neurotoxicants of significance to human health are emphasized, especially those for which metabolism and dose-responses are well well studied both in vivo and in vitro: lead, mercury, organophosphorous insecticides, polychlorinated biphenyls and dioxin, ethanol, and endogenous proteins. The goal is to set out new concepts and research directions that will hasten significant improvement in the methods and systems for in vitro neurotoxicity testing.

Environmental Neurotoxicology

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Release : 1992-02-01
Genre : Science
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Book Rating : 312/5 ( reviews)

Environmental Neurotoxicology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Environmental Neurotoxicology write by National Research Council. This book was released on 1992-02-01. Environmental Neurotoxicology available in PDF, EPUB and Kindle. Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Development of an in Vitro Neurotoxicity Assay

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Author :
Release : 1981
Genre : Neurotoxic agents
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Book Rating : /5 ( reviews)

Development of an in Vitro Neurotoxicity Assay - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Development of an in Vitro Neurotoxicity Assay write by Mary L. Barth. This book was released on 1981. Development of an in Vitro Neurotoxicity Assay available in PDF, EPUB and Kindle.

In Vitro Neurotoxicology

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Release : 2011-08-09
Genre : Medical
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Book Rating : 710/5 ( reviews)

In Vitro Neurotoxicology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook In Vitro Neurotoxicology write by Lucio G. Costa. This book was released on 2011-08-09. In Vitro Neurotoxicology available in PDF, EPUB and Kindle. In recent years, the need to develop acceptable alternatives to conventional animal testing for neurotoxicity and developmental neurotoxicity has been increasingly recognized, and much effort is being directed toward the development of alternative models, utilizing mostly mammalian cells in culture but also non-mammalian model systems. In Vitro Neurotoxicology: Methods and Protocols presents a series of cellular, biochemical, and molecular methodological protocols in the area of in vitro neurotoxicology, with an emphasis on mammalian cell culture systems. Opening with a section on methodologies for preparing several cellular systems of variable complexity, amenable for in vitro neurotoxicological studies, the thorough volume continues with coverage of methods to measure cellular death and major mechanisms, methods for assessing mechanisms of nervous system cell toxicity related to impairment of cell signaling, while a final section illustrates additional methods for assessing important nervous system processes such as cell proliferation, neuritogenesis, and synaptogenesis. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, In Vitro Neurotoxicology: Methods and Protocols serves researchers with an interest in assessing or characterizing the potential neurotoxicity of environmental contaminants, drugs, or other chemicals.