Neurotransmitter Actions in the Vertebrate Nervous System

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Release : 2012-12-06
Genre : Medical
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Book Rating : 613/5 ( reviews)

Neurotransmitter Actions in the Vertebrate Nervous System - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neurotransmitter Actions in the Vertebrate Nervous System write by Michael Rogawski. This book was released on 2012-12-06. Neurotransmitter Actions in the Vertebrate Nervous System available in PDF, EPUB and Kindle. Intercellular communication via bioactive substances occurs in virtually all multicellular systems. Chemical neurotransmission in the vertebrate nervous system represents a form of signaling of this type. The biology of chemical neurotransmission is complex, involving transmitter synthesis, transport, and release by the presynaptic neuron; signal generation in the target tissue; and mechanisms for termination of the response. The focus of this book is on one aspect of this scheme: the diverse electrophysiological effects induced by different neurotransmitters on targets cells. In recent years, astonishing progress has been made in elucidating the specific physiological signals mediated by neurotransmitters in the verte brate nervous system, yet, in our view, this has not been adequately recog nized, perhaps because the new concepts have yet to filter into neuroscience textbooks. Nevertheless, the principles of neurotransmitter action are critical to advances in many areas of neuroscience, including molecular neurobiol ogy, neurochemistry, neuropharmacology, physiological psychology, and clinical neuroscience. It was the need for a sourcebook that prompted us to engage a group of neurophysiologists to prepare the chapters in this volume. However, there was an additional reason for this book: more and more it seemed that the field, if not yet having reached maturity, at least was ap proaching adolescence, with strengths in some areas and healthy conflicts in others. At this stage of development a textbook can help to define a field, clarify problems to be resolved, and identify areas for future investigation.

Neurotransmitter Actions in the Vertebrate System

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Release : 1985
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Neurotransmitter Actions in the Vertebrate System - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neurotransmitter Actions in the Vertebrate System write by Michael A. Rogawski. This book was released on 1985. Neurotransmitter Actions in the Vertebrate System available in PDF, EPUB and Kindle.

Exploring the Vertebrate Central Cholinergic Nervous System

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Release : 2007-04-05
Genre : Science
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Book Rating : 26X/5 ( reviews)

Exploring the Vertebrate Central Cholinergic Nervous System - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Exploring the Vertebrate Central Cholinergic Nervous System write by Alexander G. Karczmar. This book was released on 2007-04-05. Exploring the Vertebrate Central Cholinergic Nervous System available in PDF, EPUB and Kindle. Even if the “weapons of mass destruction” (WMD) and, among them, stocks of organoph- phorus (OP) agents (also referred to as war gases and nerve gases) were not found in Iraq following the US-Iraq war, the relative ease with which these substances can be made from harmless precursors and the low cost of their manufacture will continue to fascinate pow- hungry, ruthless dictators, as well as multinational and international terrorists, particularly as the close relationship between the OP agents and useful insecticides makes it easy to disguise the importation and purchase of small amounts of the precursors. Indeed, the use by Saddam Hussein of a nerve gas against the Kurds and his possible employment of the OP agents during his war with Iran, and the Sarin attack in the Tokyo underground by an extremist religious set magnetized the world with respect to the OP drugs. As these drugs exert their toxicity via their cholinergic action on the nervous, particularly central nervous, system, it is no wonder that the research in the cholinergic ? eld attracts, and merits, our intense attention. These considerations underlie the signi? cance of this book, as Alex Karczmar devotes an entire chapter of Exploring the Vertebrate Central Cholinergic Nervous System to anticholinest- ases (antiChEs), and as he is an acknowledged expert in the ? eld of cholinergic toxicity as well as a consultant to the Surgeon General of the U. S. Army.

Neurotransmitter Receptors

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Release : 2013-12-12
Genre : Science
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Book Rating : 281/5 ( reviews)

Neurotransmitter Receptors - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neurotransmitter Receptors write by Sam J. Enna. This book was released on 2013-12-12. Neurotransmitter Receptors available in PDF, EPUB and Kindle. Since the discovery that neuronal transmission can be chemically mediated, a large number of compounds have been found in the mammalian central nervous system which appear to function as neurotransmitter agents. Recently, electro physiological and biochemical methods have been developed which have enabled neuroscientists to classify better the myriad of neurotransmitter receptor sites in brain and to study their properties in finer detail. As a result of these investigations, a significant number of new discoveries have been made about the mechanisms involved in neurotransmitter receptor interactions, the role neurotransmitters play in the actions of pharmacological agents and in the pathogenesis of various neuropsychiatric disorders. The present two volume text was compiled to summarize the information relating to the physiological, biochemical, pharmacological and functional characteristics of neurotransmitter receptor sites. While emphasis is placed on neurotransmitter receptors in the mammalian central nervous system, the characteristics of these receptors in other species, both vertebrate and invertebrate, are also discussed where appropriate. While these books cover the major classes of putative neurotransmitters - amino acids, peptides and biogenic amines - and are therefore broad in scope, each is discussed in a concise fashion to highlight the major points of historical and contemporary interest. In addition to outlining data, each chapter addresses current theories relating to the various aspects of receptor properties and function in an attempt to reveal the directions of future research and as a stimulus for other workers in the field.

Discovering the Brain

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Release : 1992-01-01
Genre : Medical
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Book Rating : 290/5 ( reviews)

Discovering the Brain - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Discovering the Brain write by National Academy of Sciences. This book was released on 1992-01-01. Discovering the Brain available in PDF, EPUB and Kindle. The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."