New Developments in the Pathogenesis of Rheumatoid Arthritis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook New Developments in the Pathogenesis of Rheumatoid Arthritis write by Lazaros Sakkas. This book was released on 2017-02-22. New Developments in the Pathogenesis of Rheumatoid Arthritis available in PDF, EPUB and Kindle. The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. HLA class II alleles and T cells have been implicated for many years. The discovery of anticitrullinated peptide antibodies (ACPAs), along with the effectiveness of biological treatments targeting cytokines, such as TNF-?, IL-6, and also T cells and B cells, reinforced the pathogenetic role of the respective factors. ACPAs, induced by cigarette smoking and periodontitis in individuals with HLA-DRB1 shared epitope, appear to be autoantigens that initiate the inflammatory immune response in RA. MicroRNAs, part of epigenetic mechanisms, which also include DNA methylation, and histone modification, as well as microbiota, the composition of microbes in body cavities, also appear to influence arthritis and are discussed in this book.
New Developments in the Pathogenesis of Rheumatoid Arthritis
New Developments in the Pathogenesis of Rheumatoid Arthritis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook New Developments in the Pathogenesis of Rheumatoid Arthritis write by . This book was released on 19??. New Developments in the Pathogenesis of Rheumatoid Arthritis available in PDF, EPUB and Kindle.
Rheumatology E-Book
Rheumatology E-Book - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Rheumatology E-Book write by Marc C. Hochberg. This book was released on 2018-01-08. Rheumatology E-Book available in PDF, EPUB and Kindle. Thoroughly revised and updated, the 7th Edition of Rheumatology remains a leading text in this fast-changing field, keeping you abreast of recent advances in medications, therapies, clinical trials, and much more. Dr. Mark Hochberg and his team of expert authors and editors cover everything you need to know -- from basic scientific principles to practical clinical management strategies, all in a user-friendly, accessible manner. Provides access to quick, concise videos depicting musculoskeletal ultrasound including anisotropy, "comet tail" needle artifact, rheumatoid arthritis synovitis, acute gout, and more. Uses a consistent, logical, reader-friendly format with templated content and large-scale images for efficient visual reference. Features 14 completely new chapters covering biomedical and translational science, disease and outcome assessment, including new imaging modalities and early emerging disease, clinical therapeutics, and patient management and rehabilitation. Includes updated content on the latest diagnostic perspectives and approaches to therapy including tapering down of treatment, pulmonary hypertension and scleroderma, psoriatic arthritis, and the latest oral anticoagulants. Covers hot topics such as pathogenesis and pathophysiology of axial spondyloarthritis, DXA and measurement of bone, infectious arthritis, and more. Shares the knowledge and expertise of internationally recognized rheumatoid arthritis expert and new editor, Dr. Ellen Gravallese. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Research of Pathogenesis and Novel Therapeutics in Arthritis
Research of Pathogenesis and Novel Therapeutics in Arthritis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Research of Pathogenesis and Novel Therapeutics in Arthritis write by Chih-Hsin Tang. This book was released on 2019-06-04. Research of Pathogenesis and Novel Therapeutics in Arthritis available in PDF, EPUB and Kindle. Arthritis has a high prevalence globally and includes over 100 different types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. The exact etiology of arthritis remains unclear and no cure exists. Anti-inflammatory drugs are commonly used in the treatment of arthritis but are associated with significant side effects. Novel modes of therapy and additional prognostic biomarkers are urgently needed for arthritis patients. This book summarizes and discusses the global picture of the current understanding of arthritis.
New Therapeutic Targets in Rheumatoid Arthritis
New Therapeutic Targets in Rheumatoid Arthritis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook New Therapeutic Targets in Rheumatoid Arthritis write by Paul-Peter Tak. This book was released on 2009-05-14. New Therapeutic Targets in Rheumatoid Arthritis available in PDF, EPUB and Kindle. This volume focuses on therapeutic targets that were identified after TNF blockade. All these targets have recently been registered or are currently under development for the treatment of rheumatoid arthritis. Each chapter explores the biological rationale of a distinct therapeutic target in great detail. Readers will discover the latest in vitro work, animal models, and results from clinical trials.
