Show Me the Evidence

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Release : 2014-12-01
Genre : Political Science
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Book Rating : 701/5 ( reviews)

Show Me the Evidence - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Show Me the Evidence write by Ron Haskins. This book was released on 2014-12-01. Show Me the Evidence available in PDF, EPUB and Kindle. The first comprehensive history of the Obama administration's evidence-based initiatives. From its earliest days, the Obama administration planned and enacted several initiatives to fund social programs based on rigorous evidence of success. Ron Haskins and Greg Margolis tell the story of six—spanning preschool and K-12 education, teen pregnancy, employment and training, health, and community-based programs. Readers will appreciate the fast-moving descriptions of the politics and policy debates that shaped these federal programs and the analysis of whether they will truly reshape federal social policy and greatly improve its impacts on the nation's social problems. Based on interviews with 134 individuals (including advocates, officials at the Office of Management and Budget and the Domestic Policy Council, Congressional staff, and officials in the federal agencies administering the initiatives) as well as Congressional and administration documents and news accounts, the authors examine each of the six initiatives in separate chapters. The story of each initiative includes a review of the social problem the initiative addresses; the genesis and enactment of the legislation that authorized the initiative; and the development of the procedures used by the administration to set the evidence standard and evaluation requirements—including the requirements for grant applications and awarding of grants.

Generating Evidence for Genomic Diagnostic Test Development

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Release : 2011-07-27
Genre : Medical
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Book Rating : 042/5 ( reviews)

Generating Evidence for Genomic Diagnostic Test Development - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Generating Evidence for Genomic Diagnostic Test Development write by Institute of Medicine. This book was released on 2011-07-27. Generating Evidence for Genomic Diagnostic Test Development available in PDF, EPUB and Kindle. Ten years after the sequencing of the human genome, scientists have developed genetic tests that can predict a person's response to certain drugs, estimate the risk of developing Alzheimer's disease, and make other predictions based on known links between genes and diseases. However, genetic tests have yet to become a routine part of medical care, in part because there is not enough evidence to show they help improve patients' health. The Institute of Medicine (IOM) held a workshop to explore how researchers can gather better evidence more efficiently on the clinical utility of genetic tests. Generating Evidence for Genomic Diagnostic Test Development compares the evidence that is required for decisions regarding clearance, use, and reimbursement, to the evidence that is currently generated. The report also addresses innovative and efficient ways to generate high-quality evidence, as well as barriers to generating this evidence. Generating Evidence for Genomic Diagnostic Test Development contains information that will be of great value to regulators and policymakers, payers, health-care providers, researchers, funders, and evidence-based review groups.

Clinical Applications for Next-Generation Sequencing

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Release : 2015-09-10
Genre : Science
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Book Rating : 410/5 ( reviews)

Clinical Applications for Next-Generation Sequencing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Clinical Applications for Next-Generation Sequencing write by Urszula Demkow. This book was released on 2015-09-10. Clinical Applications for Next-Generation Sequencing available in PDF, EPUB and Kindle. Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments. Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients. The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia. Fills the gap between state-of-the-art technology and evidence-based practice Provides an educational opportunity which advances patient care through the transfer of NGS to real-world patient assessment Promotes a practical tool that clinicians can apply directly to patient care Includes a systematic framework for understanding the role of NGS testing in many common and rare diseases Presents evidence regarding the important role of NGS in current diagnostic strategies

Real-World Evidence Generation and Evaluation of Therapeutics

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Release : 2017-07-05
Genre : Medical
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Book Rating : 650/5 ( reviews)

Real-World Evidence Generation and Evaluation of Therapeutics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Real-World Evidence Generation and Evaluation of Therapeutics write by National Academies of Sciences, Engineering, and Medicine. This book was released on 2017-07-05. Real-World Evidence Generation and Evaluation of Therapeutics available in PDF, EPUB and Kindle. The volume and complexity of information about individual patients is greatly increasing with use of electronic records and personal devices. Potential effects on medical product development in the context of this wealth of real-world data could be numerous and varied, ranging from the ability to determine both large-scale and patient-specific effects of treatments to the ability to assess how therapeutics affect patients' lives through measurement of lifestyle changes. In October 2016, the National Academies of Sciences, Engineering, and Medicine held a workshop to facilitate dialogue among stakeholders about the opportunities and challenges for incorporating real-world evidence into all stages in the process for the generation and evaluation of therapeutics. Participants explored unmet stakeholder needs and opportunities to generate new kinds of evidence that meet those needs. This publication summarizes the presentations and discussions from the workshop.

A Framework for K-12 Science Education

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Release : 2012-02-28
Genre : Education
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Book Rating : 459/5 ( reviews)

A Framework for K-12 Science Education - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook A Framework for K-12 Science Education write by National Research Council. This book was released on 2012-02-28. A Framework for K-12 Science Education available in PDF, EPUB and Kindle. Science, engineering, and technology permeate nearly every facet of modern life and hold the key to solving many of humanity's most pressing current and future challenges. The United States' position in the global economy is declining, in part because U.S. workers lack fundamental knowledge in these fields. To address the critical issues of U.S. competitiveness and to better prepare the workforce, A Framework for K-12 Science Education proposes a new approach to K-12 science education that will capture students' interest and provide them with the necessary foundational knowledge in the field. A Framework for K-12 Science Education outlines a broad set of expectations for students in science and engineering in grades K-12. These expectations will inform the development of new standards for K-12 science education and, subsequently, revisions to curriculum, instruction, assessment, and professional development for educators. This book identifies three dimensions that convey the core ideas and practices around which science and engineering education in these grades should be built. These three dimensions are: crosscutting concepts that unify the study of science through their common application across science and engineering; scientific and engineering practices; and disciplinary core ideas in the physical sciences, life sciences, and earth and space sciences and for engineering, technology, and the applications of science. The overarching goal is for all high school graduates to have sufficient knowledge of science and engineering to engage in public discussions on science-related issues, be careful consumers of scientific and technical information, and enter the careers of their choice. A Framework for K-12 Science Education is the first step in a process that can inform state-level decisions and achieve a research-grounded basis for improving science instruction and learning across the country. The book will guide standards developers, teachers, curriculum designers, assessment developers, state and district science administrators, and educators who teach science in informal environments.