Next Generation Sequencing Technologies and Challenges in Sequence Assembly

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Release : 2014-04-19
Genre : Science
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Book Rating : 158/5 ( reviews)

Next Generation Sequencing Technologies and Challenges in Sequence Assembly - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Next Generation Sequencing Technologies and Challenges in Sequence Assembly write by Sara El-Metwally. This book was released on 2014-04-19. Next Generation Sequencing Technologies and Challenges in Sequence Assembly available in PDF, EPUB and Kindle. The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field. This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.

Next Generation Sequencing Technologies and Challenges in Sequence Assembly

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Release : 2014-05-31
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Book Rating : 168/5 ( reviews)

Next Generation Sequencing Technologies and Challenges in Sequence Assembly - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Next Generation Sequencing Technologies and Challenges in Sequence Assembly write by M. Sc Sara El-Metwally. This book was released on 2014-05-31. Next Generation Sequencing Technologies and Challenges in Sequence Assembly available in PDF, EPUB and Kindle.

Next Generation Sequencing and Sequence Assembly

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Release : 2013-07-09
Genre : Medical
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Book Rating : 263/5 ( reviews)

Next Generation Sequencing and Sequence Assembly - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Next Generation Sequencing and Sequence Assembly write by Ali Masoudi-Nejad. This book was released on 2013-07-09. Next Generation Sequencing and Sequence Assembly available in PDF, EPUB and Kindle. The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gives a good insight to these methods for readers new to the field. Gathering information, about sequencing and assembly methods together, helps both biologists and computer scientists to get a clear idea about the field. Chapters will include information about new sequencing technologies such as ChIp-seq, ChIp-chip, and De Novo sequence assembly. ​

Next Generation Sequencing

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Release : 2016-01-14
Genre : Medical
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Book Rating : 401/5 ( reviews)

Next Generation Sequencing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Next Generation Sequencing write by Jerzy Kulski. This book was released on 2016-01-14. Next Generation Sequencing available in PDF, EPUB and Kindle. Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.

Next-Generation Sequencing and Sequence Data Analysis

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Release : 2015-11-04
Genre : Science
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Book Rating : 923/5 ( reviews)

Next-Generation Sequencing and Sequence Data Analysis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Next-Generation Sequencing and Sequence Data Analysis write by Kuo Ping Chiu. This book was released on 2015-11-04. Next-Generation Sequencing and Sequence Data Analysis available in PDF, EPUB and Kindle. Nucleic acid sequencing techniques have enabled researchers to determine the exact order of base pairs - and by extension, the information present - in the genome of living organisms. Consequently, our understanding of this information and its link to genetic expression at molecular and cellular levels has lead to rapid advances in biology, genetics, biotechnology and medicine. Next-Generation Sequencing and Sequence Data Analysis is a brief primer on DNA sequencing techniques and methods used to analyze sequence data. Readers will learn about recent concepts and methods in genomics such as sequence library preparation, cluster generation for PCR technologies, PED sequencing, genome assembly, exome sequencing, transcriptomics and more. This book serves as a textbook for students undertaking courses in bioinformatics and laboratory methods in applied biology. General readers interested in learning about DNA sequencing techniques may also benefit from the simple format of information presented in the book.