Nitric Oxide and Cancer: Pathogenesis and Therapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Nitric Oxide and Cancer: Pathogenesis and Therapy write by Benjamin Bonavida. This book was released on 2015-05-12. Nitric Oxide and Cancer: Pathogenesis and Therapy available in PDF, EPUB and Kindle. Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer.
How Tobacco Smoke Causes Disease
How Tobacco Smoke Causes Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook How Tobacco Smoke Causes Disease write by United States. Public Health Service. Office of the Surgeon General. This book was released on 2010. How Tobacco Smoke Causes Disease available in PDF, EPUB and Kindle. This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
The Link Between Inflammation and Cancer
The Link Between Inflammation and Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Link Between Inflammation and Cancer write by Angus G. Dalgleish. This book was released on 2006-03-05. The Link Between Inflammation and Cancer available in PDF, EPUB and Kindle. A link between inflammation and cancer has been established many years ago, yet it is only recently that the potential significance of this connection has become apparent. Although several examples of chronic inflammatory conditions, often induced by persistent irritation and/or infection, developing into cancer have been known for some time, there has been a notable resistance to contemplate the possibility that this association may apply in a causative way to other cancers. Examples for such progression from chronic inflammation to cancer are colon carcinoma developing with increased frequency in patients with ulcerative colitis, and the increased incidence of bladder cancer in patients suffering from chronic Schistosoma infection. Inflammation and cancer have been recognized to be linked in another context for many years, i.e., with regards to pathologies resembling chronic lacerations or 'wounds that do not heal.' More recently, the immunology of wound healing has given us clues as to the mechanistic link between inflammation and cancer, in as much as wounds and chronic inflammation turn off local cell-mediated immune responses and switch on growth factor release as well the growth of new blood vessels - angiogenesis. Both of these are features of most types of tumours, which suggest that tumours may require an immunologically shielded milieu and a growth factor-rich environment.
Ovarian Cancer
Ovarian Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ovarian Cancer write by Omer Devaja. This book was released on 2018-10-24. Ovarian Cancer available in PDF, EPUB and Kindle. Ovarian cancer management is a rapidly changing field with new treatment agents available as a result of a greater understanding of the pathogenesis of this disease. In addition, both surgical and chemotherapeutic treatment strategies are evolving to maximise response in this disease. This book brings together leading specialists from around the world to discuss and outline a variety of new concepts in ovarian cancer, ranging from molecular biology and genetics through screening to both surgical and chemotherapeutic management.
Nitric Oxide (Donor/Induced) in Chemosensitization
Nitric Oxide (Donor/Induced) in Chemosensitization - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Nitric Oxide (Donor/Induced) in Chemosensitization write by Benjamin Bonavida. This book was released on 2017-06-12. Nitric Oxide (Donor/Induced) in Chemosensitization available in PDF, EPUB and Kindle. Nitric Oxide as a Chemosensitizing Agent, Volume One is the first book to describe several reviews by authoritative scientists and clinicians on novel findings in the reversal of drug resistant cancers by the combination treatment of Nitric Oxide and sub toxic concentrations of chemotherapeutic drugs that have been reported in both in vitro, in vivo and preclinical models. The book describes the various underlying chemical, molecular and genetic mechanisms by which NO and NO reactive species mediate the anti-cancer activity, thus reducing the threshold of drug resistance and enabling chemo therapeutic drugs to induce their cytotoxic activity and reversal of resistance. This book exposes scientists and clinicians to this highly beneficial topic for research investigations and pharmaceutical companies to new avenues for R&D. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding how to use Nitric Oxide as a sensitizing agent for chemotherapy. - Brings updated information as reviewed by experts in the field - Presents expert analysis and summary of reported and novel findings and potential translational application in cancer patients - Describes molecular mechanisms with new and helpful approaches that can be used in reader investigations
