NK Cells in Cancer Immunotherapy: Successes and Challenges

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Release : 2022-12-06
Genre : Science
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Book Rating : 269/5 ( reviews)

NK Cells in Cancer Immunotherapy: Successes and Challenges - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook NK Cells in Cancer Immunotherapy: Successes and Challenges write by Anahid Jewett. This book was released on 2022-12-06. NK Cells in Cancer Immunotherapy: Successes and Challenges available in PDF, EPUB and Kindle. NK Cells in Cancer Immunotherapy: Successes and Challenges explains the latest immunotherapeutic strategies, focusing on NK cells to allow the best and precise combination treatments to cancer patients. The book provides existing background knowledge in the field of immunotherapy and discusses future areas of research required to carry out cutting-edge, validated therapies. Chapters cover advances in immunotherapeutic strategies, in particular, the use of NK cells with and without T-cell therapy in the treatment of cancer. The book is a valuable resource for cancer researchers, oncologists, graduate students and those interested in learning more about novel strategies to treat cancer patients. Immunotherapy is fast becoming the method of choice for cancer therapy. Although remarkable advances have been made in the field of immunotherapy, there are significant challenges and difficulties ahead since many of the current immunotherapeutic strategies do not provide long-lasting treatment strategies, and therefore are not very effective. Covers CAR/T and CAR/NK and adoptive NK cell therapy with and without T cell therapies Discusses basic biology of NK cells and mouse models of human cancers and the role of NK cells in metastatic cancer and in cancer stem cells Encompasses information on combination therapies using check point inhibition, adoptive transfer of cytotoxic effector cells, chemotherapeutic drugs and activating and inhibitory antibodies

Successes and Challenges of NK Immunotherapy

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Release : 2021-06-23
Genre : Science
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Book Rating : 961/5 ( reviews)

Successes and Challenges of NK Immunotherapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Successes and Challenges of NK Immunotherapy write by Benjamin Bonavida. This book was released on 2021-06-23. Successes and Challenges of NK Immunotherapy available in PDF, EPUB and Kindle. Successes and Challenges of NK Immunotherapy: Increasing Anti-tumor Efficacy describes the unique therapeutic applications of NK cells to fight cancers and eliminate the bulk and subset of cancer stem cells responsible for metastasis, relapse and recurrences. The book provides information on the development, engineering, mechanisms of action, response to various preclinical models, and applications in various clinical trials. Sections cover the development of highly engineered cytotoxic NK cells, their mechanisms of action, preclinical and clinical applications, the development and application of CAR-NK cells, and new NK-drug conjugates, also emphasizing that activated NK cells can target and kill highly resistant cancer stem cells. Written by the leading experts on NK immunotherapy worldwide, this is a valuable resource for researchers, clinicians and members of the biomedical field who are interested in understanding novel and efficient therapies to fight cancers. Discusses the unique developmental applications of NK immunotherapy against cancers, which differs greatly from other types of immunotherapies Provides up-to-date and highly relevant information through chapters written by the leading researchers in the field Presents a significant number of schematic diagrams for easy understanding and reproducibility

NK Immunotherapy: Success and Challenges

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Release : 2022-09-20
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Book Rating : 982/5 ( reviews)

NK Immunotherapy: Success and Challenges - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook NK Immunotherapy: Success and Challenges write by Maverick Davies. This book was released on 2022-09-20. NK Immunotherapy: Success and Challenges available in PDF, EPUB and Kindle. Natural killer cells (NK cells) are the lymphocytes which belong to the same family as B and T cells, because they differentiate from a common progenitor. These cells detect and control early signs of cancer, and also recognize and kill virally infected cells. Specialized natural killer cells are found in placenta and are also known to play an important role in pregnancy. To enhance the immune system, natural killer cells secrete cytokines such as IFNγ and TNFα which act on other immune cells. Activating receptors recognize the molecules which are present on the surface of infected and cancer cells and switch on the natural killer cells. This book explores all the important aspects of natural killer cells. It brings forth the role of natural killer cells in disease response. In this book, using case studies and examples, constant effort has been made to make the understanding of the difficult concepts of this field as easy and informative as possible, for the readers.

Current Perspectives, Challenges and Advances in Cell Based Therapies

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Release : 2020-03-24
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Book Rating : 643/5 ( reviews)

Current Perspectives, Challenges and Advances in Cell Based Therapies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Current Perspectives, Challenges and Advances in Cell Based Therapies write by Prashant Trikha. This book was released on 2020-03-24. Current Perspectives, Challenges and Advances in Cell Based Therapies available in PDF, EPUB and Kindle.

Critical Issues in Head and Neck Oncology

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Release : 2023-03-27
Genre : Medical
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Book Rating : 759/5 ( reviews)

Critical Issues in Head and Neck Oncology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Critical Issues in Head and Neck Oncology write by Jan B. Vermorken. This book was released on 2023-03-27. Critical Issues in Head and Neck Oncology available in PDF, EPUB and Kindle. This is an open access book. With a wealth of exciting data emerging in this rapidly evolving field this book will review the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches. In addition different disease situations are addressed including different treatment approaches in primary disease and in recurrent and/or metastatic disease as well as new developments in pathology, surgery and reconstruction techniques, new systemic therapies in salivary gland cancer, and supportive care and follow-up. All disciplines involved in the treatment of head & neck cancer are covered with a focus on translation into daily practice. The 8th-THNO is designed for medical oncologists, head and neck surgeons, radiation oncologists, otolaryngologists, and other medical professionals involved in the treatment of patients with head and neck cancer.