Novel Algorithms for Structural Molecular Biology and Proteomics

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Release : 2004
Genre : Computational biology
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Book Rating : /5 ( reviews)

Novel Algorithms for Structural Molecular Biology and Proteomics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Novel Algorithms for Structural Molecular Biology and Proteomics write by Ryan Howard Lilien. This book was released on 2004. Novel Algorithms for Structural Molecular Biology and Proteomics available in PDF, EPUB and Kindle.

Algorithms in Structural Molecular Biology

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Release : 2023-08-15
Genre : Science
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Book Rating : 798/5 ( reviews)

Algorithms in Structural Molecular Biology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Algorithms in Structural Molecular Biology write by Bruce R. Donald. This book was released on 2023-08-15. Algorithms in Structural Molecular Biology available in PDF, EPUB and Kindle. An overview of algorithms important to computational structural biology that addresses such topics as NMR and design and analysis of proteins.Using the tools of information technology to understand the molecular machinery of the cell offers both challenges and opportunities to computational scientists. Over the past decade, novel algorithms have been developed both for analyzing biological data and for synthetic biology problems such as protein engineering. This book explains the algorithmic foundations and computational approaches underlying areas of structural biology including NMR (nuclear magnetic resonance); X-ray crystallography; and the design and analysis of proteins, peptides, and small molecules. Each chapter offers a concise overview of important concepts, focusing on a key topic in the field. Four chapters offer a short course in algorithmic and computational issues related to NMR structural biology, giving the reader a useful toolkit with which to approach the fascinating yet thorny computational problems in this area. A recurrent theme is understanding the interplay between biophysical experiments and computational algorithms. The text emphasizes the mathematical foundations of structural biology while maintaining a balance between algorithms and a nuanced understanding of experimental data. Three emerging areas, particularly fertile ground for research students, are highlighted: NMR methodology, design of proteins and other molecules, and the modeling of protein flexibility. The next generation of computational structural biologists will need training in geometric algorithms, provably good approximation algorithms, scientific computation, and an array of techniques for handling noise and uncertainty in combinatorial geometry and computational biophysics. This book is an essential guide for young scientists on their way to research success in this exciting field.

Structural Proteomics And Its Impact On The Life Sciences

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Release : 2008-05-06
Genre : Science
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Book Rating : 061/5 ( reviews)

Structural Proteomics And Its Impact On The Life Sciences - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Structural Proteomics And Its Impact On The Life Sciences write by Joel L Sussman. This book was released on 2008-05-06. Structural Proteomics And Its Impact On The Life Sciences available in PDF, EPUB and Kindle. The role played by structural proteomics in the first decade of the 21st century is equivalent to that played by the Human Genome Project in the last decade of the 20th century. The development of high-throughput technologies that permit the solution of hundreds of 3D structures of individual proteins, protein-protein complexes and protein-drug complexes, just by one laboratory in a single year, will provide a knowledge base which will change the face of structural biology. This will have an immediate influence on medicinal chemistry and molecular pharmacology, as well as an increasing impact on such disciplines as neurobiology, developmental biology, immunology and molecular medicine.This book presents a state-of-the-art overview of the structural proteomics field, ranging from policy issues related to funding and goals, through the high-throughput procedures for protein production, to the solution of the structures of proteins and higher-order entities, via a multidisciplinary approach involving molecular biology, X-ray crystallography, NMR and electron microscopy, as well as bioinformatics analysis. This is the first book to provide such a comprehensive coverage of a rapidly evolving field.

Structural Bioinformatics

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Release : 2009-03-16
Genre : Science
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Book Rating : 052/5 ( reviews)

Structural Bioinformatics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Structural Bioinformatics write by Jenny Gu. This book was released on 2009-03-16. Structural Bioinformatics available in PDF, EPUB and Kindle. Structural Bioinformatics was the first major effort to show the application of the principles and basic knowledge of the larger field of bioinformatics to questions focusing on macromolecular structure, such as the prediction of protein structure and how proteins carry out cellular functions, and how the application of bioinformatics to these life science issues can improve healthcare by accelerating drug discovery and development. Designed primarily as a reference, the first edition nevertheless saw widespread use as a textbook in graduate and undergraduate university courses dealing with the theories and associated algorithms, resources, and tools used in the analysis, prediction, and theoretical underpinnings of DNA, RNA, and proteins. This new edition contains not only thorough updates of the advances in structural bioinformatics since publication of the first edition, but also features eleven new chapters dealing with frontier areas of high scientific impact, including: sampling and search techniques; use of mass spectrometry; genome functional annotation; and much more. Offering detailed coverage for practitioners while remaining accessible to the novice, Structural Bioinformatics, Second Edition is a valuable resource and an excellent textbook for a range of readers in the bioinformatics and advanced biology fields. Praise for the previous edition: "This book is a gold mine of fundamental and practical information in an area not previously well represented in book form." —Biochemistry and Molecular Education "... destined to become a classic reference work for workers at all levels in structural bioinformatics...recommended with great enthusiasm for educators, researchers, and graduate students." —BAMBED "...a useful and timely summary of a rapidly expanding field." —Nature Structural Biology "...a terrific job in this timely creation of a compilation of articles that appropriately addresses this issue." —Briefings in Bioinformatics

Algorithms in Computational Molecular Biology

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Release : 2011-04-04
Genre : Science
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Book Rating : 987/5 ( reviews)

Algorithms in Computational Molecular Biology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Algorithms in Computational Molecular Biology write by Mourad Elloumi. This book was released on 2011-04-04. Algorithms in Computational Molecular Biology available in PDF, EPUB and Kindle. This book represents the most comprehensive and up-to-date collection of information on the topic of computational molecular biology. Bringing the most recent research into the forefront of discussion, Algorithms in Computational Molecular Biology studies the most important and useful algorithms currently being used in the field, and provides related problems. It also succeeds where other titles have failed, in offering a wide range of information from the introductory fundamentals right up to the latest, most advanced levels of study.