Novel Aspects of PTHrP Physiopathology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Novel Aspects of PTHrP Physiopathology write by Claudio Luparello. This book was released on 2007. Novel Aspects of PTHrP Physiopathology available in PDF, EPUB and Kindle. The idea of this book is to attempt to provide an appropriate ground for the discussion of modern PTHrP-related issues, and for the consideration of attentive speculation and comments on current work. It is designed to intersect all the usual lines of disciplines, providing a site for presenting pertinent investigations and for discussing critical questions relevant to the entire field, thus seeking to develop a new focus and new perspectives for all those concerned with PTHrP and its pathobiology.
Hypercalcemia of Malignancy
Hypercalcemia of Malignancy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Hypercalcemia of Malignancy write by Friedhelm Raue. This book was released on 2012-12-06. Hypercalcemia of Malignancy available in PDF, EPUB and Kindle. Hypercalcemia is the most common life-threatening metabolic disorder associated with cancer. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. With a better understanding of the pathophysiology of this condition and the development of new potent drugs, capable of inhibiting bone resorption, especially bisphosphonates, the clinician will be more successful in correcting hypercalcemia in the great majority of patients.
Parathyroid Hormone - Related Protein
Parathyroid Hormone - Related Protein - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Parathyroid Hormone - Related Protein write by Bernard P. Halloran. This book was released on 1992-03-04. Parathyroid Hormone - Related Protein available in PDF, EPUB and Kindle. Since its discovery, a substantial body of information has been amassed concerning the functions of parathyroid hormone-related protein (PTHrP) in normal and malignant states. This book provides a state-of-the-art discussion of the major aspects of PTHrP biology and pathophysiology, in addition to presenting a historical perspective and discussions on the molecular biology of PTHrP, its mechanism of action, bioassays and radioimmunoassays, and its role in normal physiology. The book will be a primary resource for physicians interested in the clinical aspects of paraneoplastic hypercalcemia and mineral metabolic disorders. It will also serve as a primary resource for basic scientists in skeletal and renal physiology, tumor biology, and hormone action. PROPOSED CONTENTS: INTRODUCTION (A. BROADUS). HISTORY. Identification of Clinical Syndrome of MAH. Evidence for Unique PTH-Like Factor. ISOLATION AND PURIFICATION OF PTHrP. CHEMICAL DESCRIPTION OF PTHrP. MOLECULAR BIOLOGY OF PTHrP (D. GOLTZMAN). GENE STRUCTURE. Intron and Exon Boundaries. Identification of Promoter and Putative Regulatory Elements. Alternative Splicing. EVOLUTIONARY RELATIONSHIP TO PTH GENE. EXPRESSION OF PTHrP (M. THIEDE). EXPRESSION IN TUMOR TISSUES. EXPRESSION IN NORMAL TISSUES. EXPRESSION IN CELL CULTURE. SECRETED FORMS. ASSAY OF PTHrP AND ITS ROLE IN MAH (A. STEWART, W. BURTIS). BIO- AND RADIOIMMUNOASSAYS. SERUM CONCENTRATIONS IN NORMAL SUBJECTS AND CANCER PATIENTS. RELATIONSHIP BETWEEN EXPRESSION OF PTHRP AND HYPERCALCEMIA. EFFECTS ON TARGET TISSUES. Bone. Kidney. ROLE OF FACTORS OTHER THAN PTHrP IN MAH. MOLECULAR MECHANISM OF ACTION OF PTHrP (R. NISSENSON, G. STREWLER). RECEPTOR BINDING AND CELL SIGNALING. IMPLICATIONS FOR STRUCTURE-FUNCTION FOR PTHrP FAMILY. PTHrP IN NORMAL PHYSIOLOGY (J. MARTIN). EMBRYONIC AND NEONATAL DEVELOPMENT. LACTATION. RELATIONSHIP TO PTH.
Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Holland-Frei Cancer Medicine write by Robert C. Bast, Jr.. This book was released on 2017-03-10. Holland-Frei Cancer Medicine available in PDF, EPUB and Kindle. Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
The Parathyroids
The Parathyroids - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Parathyroids write by John P. Bilezikian. This book was released on 2001-07-21. The Parathyroids available in PDF, EPUB and Kindle. Written by world experts, this books follows upon the monumental success of the first edition of The Parathyroids, which was universally acclaimed as the best text on the subject. An authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium, The Parathyroids offers an objective and authoritative view on controversial clinical issues in this rapidly changing field. Every medical school library and virtually every major hospital library will need this book as a reference for students and clinicians. Key Features * Offers objective and authoritative reviews on controversial clinical issues * Written by world experts on parathyroid hormone and its disorders * Superb, state-of-the-art compendium in one convenient volume * Bridges basic science of parathyroid hormone to major clinical disorders * Practical information on clinical management of parathyroid hormone disorders
