Oral Drug Delivery for Modified Release Formulations - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Oral Drug Delivery for Modified Release Formulations write by Edmund S. Kostewicz. This book was released on 2022-04-04. Oral Drug Delivery for Modified Release Formulations available in PDF, EPUB and Kindle. ORAL DRUG DELIVERY FOR MODIFIED RELEASE FORMULATIONS Provides pharmaceutical development scientists with a detailed reference guide for the development of MR formulations Oral Drug Delivery for Modified Release Formulations is an up-to-date review of the key aspects of oral absorption from modified-release (MR) dosage forms. This edited volume provides in-depth coverage of the physiological factors that influence drug release and of the design and evaluation of MR formulations. Divided into three sections, the book begins by describing the gastrointestinal tract (GIT) and detailing the conditions and absorption processes occurring in the GIT that determine a formulation’s oral bioavailability. The second section explores the design of modified release formulations, covering early drug substance testing, the biopharmaceutics classification system, an array of formulation technologies that can be used for MR dosage forms, and more. The final section focuses on in vitro, in silico, and in vivo evaluation and regulatory considerations for MR formulations. Topics include biorelevant dissolution testing, preclinical evaluation, and physiologically-based pharmacokinetic modelling (PBPK) of in vivo behaviour. Featuring contributions from leading researchers with expertise in the different aspects of MR formulations, this volume: Provides authoritative coverage of physiology, physicochemical determinants, and in-vitro in-vivo correlation (IVIVC) Explains the different types of MR formulations and defines the key terms used in the field Discusses the present status of MR technologies and identifies current gaps in research Includes a summary of regulatory guidelines from both the US and the EU Shares industrial experiences and perspectives on the evaluation of MR dosage formulations Oral Drug Delivery for Modified Release Formulations is an invaluable reference and guide for researchers, industrial scientists, and graduate students in general areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.
Oral Controlled Release Formulation Design and Drug Delivery
Oral Controlled Release Formulation Design and Drug Delivery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Oral Controlled Release Formulation Design and Drug Delivery write by Hong Wen. This book was released on 2011-01-14. Oral Controlled Release Formulation Design and Drug Delivery available in PDF, EPUB and Kindle. This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.
Controlled Release in Oral Drug Delivery
Controlled Release in Oral Drug Delivery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Controlled Release in Oral Drug Delivery write by Clive G. Wilson. This book was released on 2011-09-22. Controlled Release in Oral Drug Delivery available in PDF, EPUB and Kindle. Controlled Release in Oral Drug Delivery provides focus on specific topics, complementing other books in the initial CRS series. Each chapter sets the context for the inventions described and describe the latitude that the inventions allow. In order to provide some similar look to each chapter, the coverage includes the historical overview, candidate drugs, factors influencing design and development, formulation and manufacturing and delivery system design. This volume was written along three main sections: the relevant anatomy and physiology, a discussion on candidates for oral drug delivery and the major three groups of controlled release systems: diffusion control (swelling and inert matrices); environmental control (pH sensitive coatings, time control, enzymatic control, pressure control) and finally lipidic systems.
Modified-Release Drug Delivery Technology
Modified-Release Drug Delivery Technology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Modified-Release Drug Delivery Technology write by Michael J. Rathbone. This book was released on 2002-11-07. Modified-Release Drug Delivery Technology available in PDF, EPUB and Kindle. Describing formulation challenges and their solutions in the design, development, and commercialization of modified-release drugs delivery systems, this book contains eighty papers that review recent developments in design and manufacturing techniques. It includes detailed descriptions of extended release drug products for the oral, nasal, ophthalmic, pulmonary, vaginal, dermal and transdermal pathways. With the exception of the final section addressing regulatory issues, each section covers a particular route for drug delivery and opens with an overview of the anatomical, physiological, and pharmaceutical basics of each route before moving on to cover specific technologies.
Applied Biopharmaceutics and Pharmacokinetics
Applied Biopharmaceutics and Pharmacokinetics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Applied Biopharmaceutics and Pharmacokinetics write by Leon Shargel. This book was released on 1993. Applied Biopharmaceutics and Pharmacokinetics available in PDF, EPUB and Kindle.
