Oxidative Stress and Inflammation in Experimental Models of Parkinson's Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Oxidative Stress and Inflammation in Experimental Models of Parkinson's Disease write by Carmen Ines Henze. This book was released on 2006. Oxidative Stress and Inflammation in Experimental Models of Parkinson's Disease available in PDF, EPUB and Kindle.
Studies on Experimental Models
Studies on Experimental Models - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Studies on Experimental Models write by Samar Basu. This book was released on 2011-04-13. Studies on Experimental Models available in PDF, EPUB and Kindle. There is a widespread consensus that use of antioxidants as a therapeutic approach may counteract free radical mediated pathologies. However, the role of antioxidants in normal physiology and redox signaling is still in its infancy. Since oxidative stress is related to various diseases and pathologies, scientists are eager to study the disease in humans, but it is not always ethical to study all the aspects of the disease in humans. Thus, it becomes mandatory to study the disease process and the mechanisms behind it through experimental models which generally involve animals, in vitro/cell culture studies, primates and even humans to a certain extent. Studies on Experimental Models contains data on the experimental models or review of such models of oxidative stress in various diseases. It is structured into six sections, which are as follows: diabetes, cardiovascular, neurology, ocular diseases, toxicology/environmental and in vitro/tissue culture. Each section presents a sketch of models in humans, animals and in vitro methods. Taken together, they comprise a valuable reference for basic and clinical scientists, one aimed at contributing to the advancement of oxidative stress research using appropriate animal models.
Oxidative Stress and Redox Signalling in Parkinson’s Disease
Oxidative Stress and Redox Signalling in Parkinson’s Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Oxidative Stress and Redox Signalling in Parkinson’s Disease write by Rodrigo Franco. This book was released on 2017-07-25. Oxidative Stress and Redox Signalling in Parkinson’s Disease available in PDF, EPUB and Kindle. Parkinson's Disease is the second most common neurodegenerative disorder affecting millions of people worldwide. In order to find neuroprotective strategies, a clear understanding of the mechanisms involved in the dopaminergic death of cells that progresses the disease is needed. Oxidative stress can be defined as an imbalance between the production of reactive species and the ability to detoxify them and their intermediates or by-products. Oxidative damage to lipids, proteins, and DNA has been detected in autopsies from individuals with Parkinson’s Disease and so links can be made between oxidative stress and Parkinson’s Disease pathogenesis. This book provides a thorough review of the mechanisms by which oxidative stress and redox signalling mediate Parkinson’s Disease. Opening chapters bring readers up to speed on basic knowledge regarding oxidative stress and redox signalling, Parkinson’s Disease, and neurodegeneration before the latest advances in this field are explored in detail. Topics covered in the following chapters include the role of mitochondria, dopamine metabolism, metal homeostasis, inflammation, DNA-damage and thiol-signalling. The role of genetics and gene-environment interactions are also explored before final chapters discuss the identification of potential biomarkers for diagnosis and disease progression and the future of redox/antioxidant based therapeutics. Written by recognized experts in the field, this book will be a valuable source of information for postgraduate students and academics, clinicians, toxicologists and risk assessment groups. Importantly, it presents the current research that might later lead to redox or antioxidant – based therapeutics for Parkinson’s disease.
Oxidative Stress and Neurodegenerative Disorders
Oxidative Stress and Neurodegenerative Disorders - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Oxidative Stress and Neurodegenerative Disorders write by G. Ali Qureshi. This book was released on 2007-03-22. Oxidative Stress and Neurodegenerative Disorders available in PDF, EPUB and Kindle. Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders. * Contains the latest information on the subject of neurodegenerative disorders* Reflects on various factors involved in degeneration and gives suggestions for how to tackle these problems
Oxidative Stress: How has it been Considered in the Design of New Drug Candidates for Neurodegenerative Diseases?
Oxidative Stress: How has it been Considered in the Design of New Drug Candidates for Neurodegenerative Diseases? - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Oxidative Stress: How has it been Considered in the Design of New Drug Candidates for Neurodegenerative Diseases? write by Claudio Viegas Jr. This book was released on 2021-01-22. Oxidative Stress: How has it been Considered in the Design of New Drug Candidates for Neurodegenerative Diseases? available in PDF, EPUB and Kindle.
