P38 Signaling Pathway - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook P38 Signaling Pathway write by Ana Cuenda. This book was released on 2021-09-02. P38 Signaling Pathway available in PDF, EPUB and Kindle. p38 Mitogen activated protein kinases (p38MAPK) are a group of evolutionary conserved protein kinases which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration and tumour formation. The interest in this group of protein kinases has grown continually since their discovery. Recent studies using new genetic and pharmacological tools are providing helpful information on the function of these stress-activated protein kinases and show that they have an acute impact on the development of prevalent diseases related to inflammation, diabetes, neurodegeneration, and cancer. In this Special Issue we present novel advances and review the knowledge on the identification of p38MAPK substrates, functions, and regulation; mechanisms underlying the role of p38MAPK in malignant transformation and other pathologies; and therapeutic opportunities associated with regulation of p38MAPK activity.
Stress-Activated Protein Kinases
Stress-Activated Protein Kinases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Stress-Activated Protein Kinases write by Francesc Posas. This book was released on 2008-01-24. Stress-Activated Protein Kinases available in PDF, EPUB and Kindle. In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signaling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis. Written by international experts, the book will appeal to cell biologists and biochemists.
Encyclopedia of Signaling Molecules
Encyclopedia of Signaling Molecules - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Encyclopedia of Signaling Molecules write by Sangdun Choi. This book was released on 2017-12-15. Encyclopedia of Signaling Molecules available in PDF, EPUB and Kindle. The second edition of this encyclopedia presents over 400 biologically important signaling molecules and the content is built on the core concepts of their functions along with early findings written by some of the world’s foremost experts. The molecules are described by recognized leaders in each molecule. The interactions of these single molecules in signal transduction networks will also be explored. This encyclopedia marks a new era in overview of current cellular signaling molecules for the specialist and the interested non-specialist alike. Currently, there are more than 30,000 genes in human genome. However, not all the proteins encoded by these genes work equally in order to maintain homeostasis. Understanding the important signaling molecules as completely as possible will significantly improve our research-based teaching and scientific capabilities.
P38 Signaling Pathway
P38 Signaling Pathway - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook P38 Signaling Pathway write by Ana Cuenda. This book was released on 2021. P38 Signaling Pathway available in PDF, EPUB and Kindle. P38 Mitogen activated protein kinases (p38MAPK) are a group of evolutionary conserved protein kinases which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration and tumour formation. The interest in this group of protein kinases has grown continually since their discovery. Recent studies using new genetic and pharmacological tools are providing helpful information on the function of these stress-activated protein kinases and show that they have an acute impact on the development of prevalent diseases related to inflammation, diabetes, neurodegeneration, and cancer. In this Special Issue we present novel advances and review the knowledge on the identification of p38MAPK substrates, functions, and regulation; mechanisms underlying the role of p38MAPK in malignant transformation and other pathologies; and therapeutic opportunities associated with regulation of p38MAPK activity.
Leucine-Rich Repeat Kinase 2 (LRRK2)
Leucine-Rich Repeat Kinase 2 (LRRK2) - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Leucine-Rich Repeat Kinase 2 (LRRK2) write by Hardy J. Rideout. This book was released on 2017-03-28. Leucine-Rich Repeat Kinase 2 (LRRK2) available in PDF, EPUB and Kindle. This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.
