Peptide and Protein Drug Analysis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Peptide and Protein Drug Analysis write by Ronald Reid. This book was released on 1999-11-12. Peptide and Protein Drug Analysis available in PDF, EPUB and Kindle. Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design. Provides a broad, comprehensive overview of peptides and proteins as mediators of cell movement, proliferation, differentiation, and communication. Written by more than 50 leading international authorities, Peptides and Protein Drug Analysis discusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology examines chemical purity analysis by high-pressure chromatographic, capillary electrophoretic, gel electrophoretic, and isoelectric focusing methods highlights drug design elements derived from protein folding, bioinformatics, and computational chemistry demonstrates uses of unnatural mutagenesis and combinatorial chemistry explores mass spectrometry, protein sequence, and carbohydrate analysis illustrates bioassays and other new functional analysis methods surveys spectroscopic techniques such as ultraviolet, fluorescence, Fourier transform infrared, and nuclear magnetic resonance (NMR) addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells reviews structural analysis tools such as ultracentrifugation and light, X-ray, and neutron scattering and more! Featuring over 3400 bibliographic citations and more than 500 tables, equations, and illustrations, Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical, organic, and pharmaceutical chemists; cell and molecular biologists; biochemists; and upper-level undergraduate and graduate students in these disciplines.
Stability and Characterization of Protein and Peptide Drugs
Stability and Characterization of Protein and Peptide Drugs - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Stability and Characterization of Protein and Peptide Drugs write by Rodney Pearlman. This book was released on 2013-06-29. Stability and Characterization of Protein and Peptide Drugs available in PDF, EPUB and Kindle. This is the first volume to make available specific case histories of therapeutic proteins and peptides that have been marketed or are currently under clinical testing. The editors have selected a wide range of molecules derived from monoclonal antibodies, recombinant DNA, and natural and chemical sources to provide formulation scientists with practical examples of the development of pharmaceutical products.
Peptide and Protein Drug Delivery
Peptide and Protein Drug Delivery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Peptide and Protein Drug Delivery write by Vincent Lee. This book was released on 1990-11-19. Peptide and Protein Drug Delivery available in PDF, EPUB and Kindle. This reference/text covers fundamentals of peptide and protein drug delivery, including such considerations as synthesis, physical chemistry and biochemistry, analysis, proteolytic and transport constraints, pharmacokinetics, and pharmacodynamics; bioavailability from routes of administration, detai
Protein and Peptide Mass Spectrometry in Drug Discovery
Protein and Peptide Mass Spectrometry in Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein and Peptide Mass Spectrometry in Drug Discovery write by Michael L. Gross. This book was released on 2011-09-26. Protein and Peptide Mass Spectrometry in Drug Discovery available in PDF, EPUB and Kindle. The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing together the work of experts in academia and industry, Protein and Peptide Mass Spectrometry in Drug Discovery highlights current analytical approaches, industry practices, and modern strategies for the characterization of both peptides and proteins in drug discovery. Illustrating the critical role MS technology plays in characterizing target proteins and protein products, the methods used, ion mobility, and the use of microwave radiation to speed proteolysis, the book also covers important emerging applications for neuroproteomics and antigenic peptides. Placing an emphasis on the pharmaceutical industry, the book stresses practice and applications, presenting real-world examples covering the most recent advances in mass spectrometry, and providing an invaluable resource for pharmaceutical scientists in industry and academia, analytical and bioanalytical chemists, and researchers in protein science and proteomics.
Peptide Chemistry and Drug Design
Peptide Chemistry and Drug Design - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Peptide Chemistry and Drug Design write by Ben M. Dunn. This book was released on 2015-02-02. Peptide Chemistry and Drug Design available in PDF, EPUB and Kindle. This book focuses on peptides as drugs, a growing area ofpharmaceutical research and development. It helps readers solveproblems of discovering, developing, producing, and deliveringpeptide-based drugs. • Identifies promising new areas in peptide drugdiscovery • Includes chapters on discovery from natural sources,metabolic modification, and drug delivery • Overviews separation methods and techniques foranalysis, bond formation, and purification • Offers readers both a professional reference and atext or resource for graduate-level students
