Peptide and protein surface recognition by tetraguanidinium compounds - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Peptide and protein surface recognition by tetraguanidinium compounds write by Xavier Salvatella i Giralt. This book was released on 2002. Peptide and protein surface recognition by tetraguanidinium compounds available in PDF, EPUB and Kindle.
Understanding Biology Using Peptides
Understanding Biology Using Peptides - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Understanding Biology Using Peptides write by Sylvie E. Blondelle. This book was released on 2007-10-23. Understanding Biology Using Peptides available in PDF, EPUB and Kindle. This book represents proceedings of the 19th American Peptide Symposium. It highlights many of the recent developments in peptide science, with a particular emphasis on how these advances are being applied to basic problems in biology and medicine. Specific topics covered include novel synthetic strategies, peptides in biological signaling, post-translational modifications of peptides and proteins, and peptide quaternary structure in material science and disease.
Protein Surface Recognition
Protein Surface Recognition - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Surface Recognition write by Ernest Giralt. This book was released on 2011-07-07. Protein Surface Recognition available in PDF, EPUB and Kindle. A new perspective on the design of molecular therapeutics is emerging. This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aim of inhibiting protein/protein interactions. The successful development of compounds able to inhibit these interactions offers a unique chance to selectively intervene in a large number of key cellular processes related to human disease. Protein Surface Recognition presents a detailed treatment of this strategy, with topics including: an extended survey of protein-protein interactions that are key players in human disease and biology and the potential for therapeutics derived from this new perspective the fundamental physical issues that surround protein-protein interactions that must be considered when designing ligands for protein surfaces examples of protein surface-small molecule interactions, including treatments of protein-natural product interactions, protein-interface peptides, and rational approaches to protein surface recognition from model to biological systems a survey of techniques that will be integral to the discovery of new small molecule protein surface binders, from high throughput synthesis and screening techniques to in silico and in vitro methods for the discovery of novel protein ligands. Protein Surface Recognition provides an intellectual “tool-kit” for investigators in medicinal and bioorganic chemistry looking to exploit this emerging paradigm in drug discovery.
CPP, Cell-Penetrating Peptides
CPP, Cell-Penetrating Peptides - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook CPP, Cell-Penetrating Peptides write by Ülo Langel. This book was released on 2019-06-03. CPP, Cell-Penetrating Peptides available in PDF, EPUB and Kindle. In this book, a summary and update of the most important areas of CPP research are presented, whilst raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo are discussed. Therapeutic potential of CPPs and commercial developments are discussed. The monograph is written for researchers and students in the field.
Supramolecular Systems in Biomedical Fields
Supramolecular Systems in Biomedical Fields - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Supramolecular Systems in Biomedical Fields write by Hans-Jorg Schneider. This book was released on 2013-09-06. Supramolecular Systems in Biomedical Fields available in PDF, EPUB and Kindle. Non-covalent interactions, which are the heart of supramolecular chemistry are also the basis of most important functions of living systems. The ability to apply supramolecular chemistry principles to the life sciences, such as designing synthetic host compounds to selectively interact within biological targets, has gained wide appeal due the vast number of potential applications. Supramolecular Systems for Biomedical Fields provides in sixteen chapters a comprehensive overview of these applications. Each chapter covers a specific topic and is written by internationally renowned experts in that area. Sensing of bioactive inorganic ions and organic substrates is the focus of several contributions, as well as interactions with proteins and nucleic acids. Specific chapters are devoted to cyclodextrins, calixarenes and cucurbiturils as most frequently used receptors, including applications such as drug delivery and protection, gene transfer and others. Other chapters address the use of combinatorial libraries, molecular imprinting techniques, enzyme assays, supramolecular gels, bioimaging, drug activation, photodynamic therapy, and antitumour metal complexes. This timely publication will appeal to graduate students and researchers from chemical, pharmaceutical, biological, and medicinal fields interested in the supramolecular chemistry of biological systems and their practical potentials.
