Side Reactions in Peptide Synthesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Side Reactions in Peptide Synthesis write by Yi Yang. This book was released on 2015-09-01. Side Reactions in Peptide Synthesis available in PDF, EPUB and Kindle. Side Reactions in Peptide Synthesis, based on the author’s academic and industrial experience, and backed by a thorough review of the current literature, provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis. This valuable handbook is ideal for research and process chemists working with peptide synthesis in diverse settings across academic, biotech, and pharmaceutical research and development. While peptide chemistry is increasingly prevalent, common side reactions and their causes are often poorly understood or anticipated, causing unnecessary waste of materials and delay. Each chapter discusses common side reactions through detailed chemical equations, proposed mechanisms (if any), theoretical background, and finally, a variety of possible solutions to avoid or alleviate the specified side reaction. Provides a systematic examination on how to troubleshoot and minimize the most frequent side reactions in peptide synthesis Gives chemists the background information and the practical tools they need to successfully troubleshoot and improve results Includes optimization-oriented analysis of side reactions in peptide synthesis for improved industrial process development in peptidyl API (active pharmaceutical ingredient) production Answers the growing, global need for improved, replicable processes to avoid impurities and maintain the integrity of the end product. Presents a thorough discussion of critical factors in peptide synthesis which are often neglected or underestimated by chemists Covers solid phase and solution phase methodologies, and provides abundant references for further exploration
Peptides 2015
Peptides 2015 - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Peptides 2015 write by Ved Srivastava. This book was released on 2015-08-21. Peptides 2015 available in PDF, EPUB and Kindle. Proceedings of the 24th American Peptide Symposium in Orlando, Florida, June, 2015
Peptide Chemistry and Drug Design
Peptide Chemistry and Drug Design - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Peptide Chemistry and Drug Design write by Ben M. Dunn. This book was released on 2015-02-02. Peptide Chemistry and Drug Design available in PDF, EPUB and Kindle. This book focuses on peptides as drugs, a growing area ofpharmaceutical research and development. It helps readers solveproblems of discovering, developing, producing, and deliveringpeptide-based drugs. • Identifies promising new areas in peptide drugdiscovery • Includes chapters on discovery from natural sources,metabolic modification, and drug delivery • Overviews separation methods and techniques foranalysis, bond formation, and purification • Offers readers both a professional reference and atext or resource for graduate-level students
Cell-Penetrating Peptides
Cell-Penetrating Peptides - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cell-Penetrating Peptides write by Ülo Langel. This book was released on 2015-07-24. Cell-Penetrating Peptides available in PDF, EPUB and Kindle. Divided into three parts this volume summarizes the most important areas of Cell-Penetrating Peptides (CPP) research . Part one briefly presents the historical background of CPP studies and the classifications of the available CPPs, and then summarizes the approaches for prediction of novel CPPs. Part two mainly describes the methods for studies of “naked” CPPs, that is, CPPs without conjugated cargos. Last but not least part three presents a representative and brief summary of functionality issues of CPPs, both in vitro and in vivo. As a volume in the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Concise and easy-to-use, Cell-Penetrating Peptides: Methods and Protocols, Second Edition hopes to raise relevant questions for further development.
Introduction to Protein Mass Spectrometry
Introduction to Protein Mass Spectrometry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Introduction to Protein Mass Spectrometry write by Pradip K. Ghosh. This book was released on 2015-12-10. Introduction to Protein Mass Spectrometry available in PDF, EPUB and Kindle. Introduction to Protein Mass Spectrometry provides a comprehensive overview of this increasingly important, yet complex, analytical technique. Unlike many other methods which automatically yield an absolutely unique protein name as output, protein mass spectrometry generally requires a deduction of protein identity from determination of peptide fragmentation products. This book enables readers to both understand, and appreciate, how determinations about protein identity from mass spectrometric data are made. Coverage begins with the technical basics, including preparations, instruments, and spectrometric analysis of peptides and proteins, before exploring applied use in biological applications, bioinformatics, database, and software resources. Citing the most recent and relevant work in the field of biological mass spectrometry, the book is written for researchers and scientists new to the field, but is also an ideal resource for those hoping to hone their analytical abilities. Offers introductory information for scientists and researchers new to the field, as well as advanced insight into the critical assessment of computer-analyzed mass spectrometric results and their current limitations Provides examples of commonly-used MS instruments from Bruker, Applied Biosystems, JEOL, Thermo Scientific/Thermo Fisher Scientific, IU, and Waters Includes biological applications and exploration of analytical tools and databases for bioinformatics
