Pharmaceutical Process Chemistry

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Release : 2010-12-09
Genre : Technology & Engineering
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Book Rating : 693/5 ( reviews)

Pharmaceutical Process Chemistry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pharmaceutical Process Chemistry write by Takayuki Shioiri. This book was released on 2010-12-09. Pharmaceutical Process Chemistry available in PDF, EPUB and Kindle. Covering the whole area of process chemistry in the pharmaceutical industry, this monograph provides the essential knowledge on the basic chemistry needed for future development and key industrial techniques, as well as morphology, engineering and regulatory compliances. Application-oriented and well structured, the authors include recent examples of excellent industrial production of active pharmaceutical ingredients.

Pharmaceutical Process Chemistry for Synthesis

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Release : 2011-02-23
Genre : Science
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Book Rating : 869/5 ( reviews)

Pharmaceutical Process Chemistry for Synthesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pharmaceutical Process Chemistry for Synthesis write by Peter J. Harrington. This book was released on 2011-02-23. Pharmaceutical Process Chemistry for Synthesis available in PDF, EPUB and Kindle. There is a need to explain that generic versions of a drug may not be manufactured by the same process as brand-name drugs and that the different processes may have dramatically different environmental impacts. Two global forces are at odds today—the push for "greener" processes and the push for lower drug prices. This book brings this conflict into sharp focus by discussing in detail the published process chemistry for top-selling small molecule drugs. Providing insights about process route selection, choice of reagents, and reaction conditions, Pharmaceutical Process Chemistry for Synthesis guides process chemists in identifying best processes for manufacturing these blockbuster drugs as they lose patent protection. Further, it highlights the strategies and methodology that might be useful for expediting the process research and development of the blockbusters of the future. Written from a refreshingly objective perspective, this book is essential for process chemists who need to devise practical syntheses for increasingly complex drugs in a constantly decreasing time frame.

Process Chemistry in the Pharmaceutical Industry

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Release : 1999-05-06
Genre : Medical
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Book Rating : 814/5 ( reviews)

Process Chemistry in the Pharmaceutical Industry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Process Chemistry in the Pharmaceutical Industry write by Kumar Gadamasetti. This book was released on 1999-05-06. Process Chemistry in the Pharmaceutical Industry available in PDF, EPUB and Kindle. Providing guidance for chemists and other scientists entering pharmaceutical discovery and development, this up-to-the-minute reference presents contributions from an international group of nearly 50 renowned researchers—offering a solid grounding in synthetic and physical organic chemistry, and clarifying the roles of various specialties in the development of new drugs. Featuring over 1000 references, tables, and illustrations, Process Chemistry in the Pharmaceutical Industry is sure to find its way to the bookshelves of organic, physical, analytical, process, and medicinal chemists and biochemists; pharmacists; and upper-level undergraduate and graduate students in these disciplines.

Process Chemistry in the Pharmaceutical Industry, Volume 2

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Release : 2007-12-10
Genre : Science
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Book Rating : 358/5 ( reviews)

Process Chemistry in the Pharmaceutical Industry, Volume 2 - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Process Chemistry in the Pharmaceutical Industry, Volume 2 write by Kumar Gadamasetti. This book was released on 2007-12-10. Process Chemistry in the Pharmaceutical Industry, Volume 2 available in PDF, EPUB and Kindle. As pharmaceutical companies strive to develop safer medicines at a lower cost, they must keep pace with the rapid growth of technology and research methodologies. Defying the misconception of process chemistry as mere scale-up work, Process Chemistry in the Pharmaceutical Industry, Vol. 2: Challenges in an Ever Changing Climate explor

Pharmaceutical Process Development

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Release : 2011-08-17
Genre : Science
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Book Rating : 074/5 ( reviews)

Pharmaceutical Process Development - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pharmaceutical Process Development write by John Blacker. This book was released on 2011-08-17. Pharmaceutical Process Development available in PDF, EPUB and Kindle. Pharmaceutical process research and development is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted on the manufacture of pharmaceuticals. In 15 concise chapters the book covers such diverse subjects as route selection and economics, the interface with medicinal chemistry, the impact of green chemistry, safety, the crucial role of physical organic measurements in gaining a deeper understanding of chemical behaviour, the role of the analyst, new tools and innovations in reactor design, purification and separation, solid state chemistry and its role in formulation. The book ends with an assessment of future trends and challenges. The book provides a valuable overview of: both early and late stage chemical development, how safe and scaleable synthetic routes are designed, selected and developed, the importance of the chemical engineering, analytical and manufacturing interfaces, the key enabling technologies, including catalysis and biocatalysis, the importance of the green chemical perspective and solid form issues. The book, written and edited by experts in the field, is a contemporary, holistic treatise, with a logical sequence for process development and mini-case histories within the chapters to bring alive different aspects of the process. It is completely pharmaceutical themed, encompassing all essential aspects, from route and reagent selection to manufacture of the active compound. The book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry. It informs them about the breadth of the work carried out in chemical research and development departments, and gives them a feel for the challenges involved in the job. The book is also of value to academics who often understand the drug discovery arena, but have far less appreciation of the drug development area, and are thus unable to advise their students about the relative merits of careers in chemical development versus discovery.