Phthalates and Cumulative Risk Assessment - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Phthalates and Cumulative Risk Assessment write by National Research Council. This book was released on 2008-12-19. Phthalates and Cumulative Risk Assessment available in PDF, EPUB and Kindle. People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Phthalates and Cumulative Risk Assessment
Phthalates and Cumulative Risk Assessment - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Phthalates and Cumulative Risk Assessment write by National Research Council. This book was released on 2009-01-19. Phthalates and Cumulative Risk Assessment available in PDF, EPUB and Kindle. People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Phthalates and Cumulative Risk Assessment - The Tasks Ahead
Phthalates and Cumulative Risk Assessment - The Tasks Ahead - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Phthalates and Cumulative Risk Assessment - The Tasks Ahead write by . This book was released on 2008. Phthalates and Cumulative Risk Assessment - The Tasks Ahead available in PDF, EPUB and Kindle.
Science and Decisions
Science and Decisions - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Science and Decisions write by National Research Council. This book was released on 2009-03-24. Science and Decisions available in PDF, EPUB and Kindle. Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.
Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals
Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals write by National Academies of Sciences, Engineering, and Medicine. This book was released on 2017-08-14. Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals available in PDF, EPUB and Kindle. To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.
