Artemisinin-Based and Other Antimalarials

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Release : 2017-11-28
Genre : Science
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Book Rating : 116/5 ( reviews)

Artemisinin-Based and Other Antimalarials - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Artemisinin-Based and Other Antimalarials write by Guoqiao Li. This book was released on 2017-11-28. Artemisinin-Based and Other Antimalarials available in PDF, EPUB and Kindle. Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery

Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis

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Release : 2020-04-24
Genre : Medical
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Book Rating : 104/5 ( reviews)

Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis write by National Academies of Sciences, Engineering, and Medicine. This book was released on 2020-04-24. Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis available in PDF, EPUB and Kindle. Among the many who serve in the United States Armed Forces and who are deployed to distant locations around the world, myriad health threats are encountered. In addition to those associated with the disruption of their home life and potential for combat, they may face distinctive disease threats that are specific to the locations to which they are deployed. U.S. forces have been deployed many times over the years to areas in which malaria is endemic, including in parts of Afghanistan and Iraq. Department of Defense (DoD) policy requires that antimalarial drugs be issued and regimens adhered to for deployments to malaria-endemic areas. Policies directing which should be used as first and as second-line agents have evolved over time based on new data regarding adverse events or precautions for specific underlying health conditions, areas of deployment, and other operational factors At the request of the Veterans Administration, Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis assesses the scientific evidence regarding the potential for long-term health effects resulting from the use of antimalarial drugs that were approved by FDA or used by U.S. service members for malaria prophylaxis, with a focus on mefloquine, tafenoquine, and other antimalarial drugs that have been used by DoD in the past 25 years. This report offers conclusions based on available evidence regarding associations of persistent or latent adverse events.

Saving Lives, Buying Time

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Release : 2004-09-09
Genre : Medical
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Book Rating : 938/5 ( reviews)

Saving Lives, Buying Time - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Saving Lives, Buying Time write by Institute of Medicine. This book was released on 2004-09-09. Saving Lives, Buying Time available in PDF, EPUB and Kindle. For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

World Malaria Report 2014

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Release : 2015-07-07
Genre : Medical
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Book Rating : 830/5 ( reviews)

World Malaria Report 2014 - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook World Malaria Report 2014 write by World Health Organization. This book was released on 2015-07-07. World Malaria Report 2014 available in PDF, EPUB and Kindle. The World malaria report 2014 summarizes information received from 97 malaria endemic countries and other sources and updates the analyses presented in 2013. It assesses global and regional malaria trends highlights progress made towards global targets and describes opportunities and challenges in controlling and eliminating the disease. Most of the data presented in this report are for 2013.

Guidelines for the Treatment of Malaria

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Release : 2010
Genre : Medical
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Book Rating : 928/5 ( reviews)

Guidelines for the Treatment of Malaria - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Guidelines for the Treatment of Malaria write by World Health Organization. This book was released on 2010. Guidelines for the Treatment of Malaria available in PDF, EPUB and Kindle. "The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV positive, travellers from non-malaria endemic regions) and in complex emergency situations and severe malaria."--Publisher's description.