Plant Molecular Farming for the Production of Next-Generation Vaccines and Biologics – Prospects and Challenges - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Plant Molecular Farming for the Production of Next-Generation Vaccines and Biologics – Prospects and Challenges write by . This book was released on 2024-03-11. Plant Molecular Farming for the Production of Next-Generation Vaccines and Biologics – Prospects and Challenges available in PDF, EPUB and Kindle. Infectious diseases are still a major threat to public health. The vaccine remains the most important and safer way of combating infectious diseases. Therefore, there is an urgent need to look for new ways of vaccine generation that can cut down production costs and processing time. The development of rDNA technology allows the expression and purification of proteins in unlimited quantity, thus opening an avenue for the development of protein-based vaccines as a prophylactic measure against infectious diseases. Recombinant therapeutic proteins derived from biological sources, including mammalian cells, microorganisms, suspension cultures, or genetically modified organisms by employing biotechnological processes, are widely used in clinical applications, especially for the treatment and prevention of human or veterinary infections. Since the development of human insulin by utilizing recombinant DNA technology in E. coli in the 1980s, the recombinant therapeutic protein production field has significantly grown and gained major attention. Plant molecular farming, the production of biologics in plant cells or transgenic plants, could offer a cost-effective adaptable strategy to produce biologics, particularly in low-resource settings. Molecular farming-based strategies could provide an alternative strategy to traditional biologics or vaccine production, enabling rapid development, effective deployment, and safe administration of vaccines. The concept of PMF was initially documented three decades back when recombinant growth hormone was produced in tobacco and sunflower plants. Even with such a long history of significant advantages and several proof-of-concept studies, very few plant-derived therapeutic products have been clinically translated. However, the recent progress around the approval of the plant-based biopharmaceutical ZMapp by the FDA, Medicago’s COVID-19 vaccine by Health Canada, and the safety of a few plant-derived vaccines in clinical trials have displayed the potential of a plant platform for biopharmaceutical production. Furthermore, constant efforts are being made with respect to the optimization of expression techniques, downstream processing, and defining standard guidelines for plant products to make an impact of plant-derived products on an array of applications.
Environmental Effects of Transgenic Plants
Environmental Effects of Transgenic Plants - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Environmental Effects of Transgenic Plants write by National Research Council. This book was released on 2002-02-22. Environmental Effects of Transgenic Plants available in PDF, EPUB and Kindle. Transgenic crops offer the promise of increased agricultural productivity and better quality foods. But they also raise the specter of harmful environmental effects. In this new book, a panel of experts examines: • Similarities and differences between crops developed by conventional and transgenic methods • Potential for commercialized transgenic crops to change both agricultural and nonagricultural landscapes • How well the U.S. government is regulating transgenic crops to avoid any negative effects. Environmental Effects of Transgenic Plants provides a wealth of information about transgenic processes, previous experience with the introduction of novel crops, principles of risk assessment and management, the science behind current regulatory schemes, issues in monitoring transgenic products already on the market, and more. The book discusses public involvementâ€"and public confidenceâ€"in biotechnology regulation. And it looks to the future, exploring the potential of genetic engineering and the prospects for environmental effects.
Molecular Pharming
Molecular Pharming - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Pharming write by Allison R. Kermode. This book was released on 2018-03-12. Molecular Pharming available in PDF, EPUB and Kindle. A single volume collection that surveys the exciting field of plant-made pharmaceuticals and industrial proteins This comprehensive book communicates the recent advances and exciting potential for the expanding area of plant biotechnology and is divided into six sections. The first three sections look at the current status of the field, and advances in plant platforms and strategies for improving yields, downstream processing, and controlling post-translational modifications of plant-made recombinant proteins. Section four reviews high-value industrial and pharmacological proteins that are successfully being produced in established and emerging plant platforms. The fifth section looks at regulatory challenges facing the expansion of the field. The final section turns its focus toward small molecule therapeutics, drug screening, plant specialized metabolites, and plants as model organisms to study human disease processes. Molecular Pharming: Applications, Challenges and Emerging Areas offers in-depth coverage of molecular biology of plant expression systems and manipulation of glycosylation processes in plants; plant platforms, subcellular targeting, recovery, and downstream processing; plant-derived protein pharmaceuticals and case studies; regulatory issues; and emerging areas. It is a valuable resource for researchers that are in the field of plant molecular pharming, as well as for those conducting basic research in gene expression, protein quality control, and other subjects relevant to molecular and cellular biology. Broad ranging coverage of a key area of plant biotechnology Describes efforts to produce pharmaceutical and industrial proteins in plants Provides reviews of recent advances and technology breakthroughs Assesses realities of regulatory and cost hurdles Forward looking with coverage of small molecule technologies and the use of plants as models of human disease processes Providing wide-ranging and unique coverage, Molecular Pharming: Applications, Challenges and Emerging Areas will be of great interest to the plant science, plant biotechnology, protein science, and pharmacological communities.
Sustainable Food Production
Sustainable Food Production - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Sustainable Food Production write by Paul Christou. This book was released on 2012-12-05. Sustainable Food Production available in PDF, EPUB and Kindle. Gathering some 90 entries from the Encyclopedia of Sustainability Science and Technology, this book covers animal breeding and genetics for food, crop science and technology, ocean farming and sustainable aquaculture, transgenic livestock for food and more.
Proceedings of ISPMF 2018 - Plant Molecular Farming
Proceedings of ISPMF 2018 - Plant Molecular Farming - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Proceedings of ISPMF 2018 - Plant Molecular Farming write by Anneli Ritala. This book was released on 2020-06-16. Proceedings of ISPMF 2018 - Plant Molecular Farming available in PDF, EPUB and Kindle.
