Polymeric Gene Delivery Systems

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Release : 2018-09-04
Genre : Technology & Engineering
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Book Rating : 668/5 ( reviews)

Polymeric Gene Delivery Systems - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Polymeric Gene Delivery Systems write by Yiyun Cheng. This book was released on 2018-09-04. Polymeric Gene Delivery Systems available in PDF, EPUB and Kindle. ​The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. The chapter "Polymeric Nanoparticle-Mediated Gene Delivery for Lung Cancer Treatment" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Polymers and Nanomaterials for Gene Therapy

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Release : 2016-01-09
Genre : Science
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Book Rating : 210/5 ( reviews)

Polymers and Nanomaterials for Gene Therapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Polymers and Nanomaterials for Gene Therapy write by Ravin Narain. This book was released on 2016-01-09. Polymers and Nanomaterials for Gene Therapy available in PDF, EPUB and Kindle. Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. - Explores current challenges in the research of genetic diseases - Discusses polymers for gene therapy and their function in designing advanced materials - Provides examples of organic and inorganic nanomaterials for gene therapy - Includes labeling, targeting, and assays - Looks at characterization, physico-(bio)chemical properties, and applications

Polymeric Drug Delivery Systems

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Release : 2005-04-12
Genre : Medical
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Book Rating : 327/5 ( reviews)

Polymeric Drug Delivery Systems - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Polymeric Drug Delivery Systems write by Glen S. Kwon. This book was released on 2005-04-12. Polymeric Drug Delivery Systems available in PDF, EPUB and Kindle. Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.

Polymers in Drug Delivery

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Release : 2006-05-19
Genre : Medical
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Book Rating : 248/5 ( reviews)

Polymers in Drug Delivery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Polymers in Drug Delivery write by Ijeoma F. Uchegbu. This book was released on 2006-05-19. Polymers in Drug Delivery available in PDF, EPUB and Kindle. Together, the nano explosion and the genomic revolution are ushering in a new frontier in drug delivery. In recent years we've seen how polymers can play a crucial role in controlling the rate of drug release, enhancing solubility and uptake, and limiting degradation and toxicity. In the very near future, they may well be used to deliver gene thera

Polymers in Therapeutic Delivery

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Release : 2021-04-30
Genre : Medical
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Book Rating : 145/5 ( reviews)

Polymers in Therapeutic Delivery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Polymers in Therapeutic Delivery write by Associate Professor in the Chemistry Department Tomoko Fujiwara. This book was released on 2021-04-30. Polymers in Therapeutic Delivery available in PDF, EPUB and Kindle. Polymer-based systems hold great promise for the delivery of genes and drugs, as polymers can be designed and modified to meet new challenges.