Preclinical Evaluation of Cardiotoxicity Associated with Vascular Disrupting Agents Used for the Treatment of Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Preclinical Evaluation of Cardiotoxicity Associated with Vascular Disrupting Agents Used for the Treatment of Cancer write by Asma K. I. Mohamed. This book was released on 2021. Preclinical Evaluation of Cardiotoxicity Associated with Vascular Disrupting Agents Used for the Treatment of Cancer available in PDF, EPUB and Kindle.
Radiotherapy in Clinical Practice
Radiotherapy in Clinical Practice - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Radiotherapy in Clinical Practice write by H. F. Hope-Stone. This book was released on 1986. Radiotherapy in Clinical Practice available in PDF, EPUB and Kindle.
Cell Surface Proteases
Cell Surface Proteases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cell Surface Proteases write by . This book was released on 2003-05-03. Cell Surface Proteases available in PDF, EPUB and Kindle. Cell Surface Proteases provides a comprehensive overview of these important enzymes that catalyze the hydrolysis of a protein as it degrades to a simpler substance. In the 1990s, an explosion of new discoveries shed light on the role of cell surface proteases and extended it beyond degradation of extracellular matrix components to include its influence on growth factors, cell signaling, and other cellular events. This volume unites the scientific literature from across disciplines and teases out unified themes of interactions between cell surface proteases and interconnecting cell surface-related systems -- including integrins and other adhesion molecules. Scientists and students involved in developmental biology, cell biology and disease processes will find this an indispensable resource. * Provides an overview of the entire field of cell surface proteases in a single volume* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine * A thematic volume in the longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
Brain and Heart Dynamics
Brain and Heart Dynamics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Brain and Heart Dynamics write by Stefano Govoni. This book was released on 2020-07-31. Brain and Heart Dynamics available in PDF, EPUB and Kindle. This ambitious and comprehensive handbook represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest. Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling. Written by leading international experts in their respective research areas, the book presents a variety of perspectives on the core topic: from social and philosophical to gender-related aspects. It is designed for a broad readership and includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease.
Innovations for Next-Generation Antibody-Drug Conjugates
Innovations for Next-Generation Antibody-Drug Conjugates - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Innovations for Next-Generation Antibody-Drug Conjugates write by Marc Damelin. This book was released on 2018-05-29. Innovations for Next-Generation Antibody-Drug Conjugates available in PDF, EPUB and Kindle. Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
