Pathophysiology of Headaches - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pathophysiology of Headaches write by Messoud Ashina. This book was released on 2015-04-14. Pathophysiology of Headaches available in PDF, EPUB and Kindle. This book provides a detailed overview of the current state of knowledge regarding the pathophysiology of both primary headaches – migraine, tension-type headache (TTH), and cluster headache – and the very important and frequent type of secondary headache, medication overuse headache (MOH). After an introductory chapter describing relevant neuroanatomy and vascular anatomy, the evidence gained from animal models regarding the pathophysiology of migraine and the other primary headaches is reviewed. Knowledge of the genetic component in the different types of headache is then examined with reference to recent evidence, for example regarding the implication of the trigeminovascular system and cortical spreading depression in migraine. Detailed information is provided on insights into primary headaches from imaging studies, including functional magnetic resonance imaging and positron emission tomography and on their neurophysiology and biochemistry. A further series of important chapters describe present knowledge of the pathophysiology of each specific type of headache and consider future directions. Written by acknowledged experts in their fields from Europe and the United States, clinicians and students will find Pathophysiology of Headaches to be an excellent source of up-to-date information on why patients experience headaches. In addition, it will be of value for pain researchers investigating the underlying mechanisms of headache.
Drug-Induced Headache
Drug-Induced Headache - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Drug-Induced Headache write by Hans-Christoph Diener. This book was released on 2012-12-06. Drug-Induced Headache available in PDF, EPUB and Kindle. M. WILKINSON Patients with frequent or daily headaches pose a very difficult problem for the physician who has to treat them, particularly as many patients think that there should be a medicine or medicines which give them instant relief. In the search for the compound which would meet this very natural desire, many drugs have been manufactured and the temptation for the physician is either to increase the dose of a drug which seems to be, at any rate, partially effective, or to add one or more drugs to those which the patient is already taking. Although there have been some references to the dangers of overdosage of drugs for migraine in the past, it was not until relatively recently that it was recognized that drugs given for the relief of headache, if taken injudiciously, may themselves cause headache. The first drugs to be implicated in this way were ergotamine and phenazone. In the case of ergotamine tartrate, the dangers of ergotism were well known as this was a disorder which had been known and written about for many years. In the treatment of headache, fully blown ergotism is rare and in recent years has usually been due to self-medication in doses much greater than those prescribed although there are a few recorded cases where toxic amounts have been given.
Pain
Pain - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pain write by . This book was released on 2001. Pain available in PDF, EPUB and Kindle.
Neurology in Clinical Practice
Neurology in Clinical Practice - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neurology in Clinical Practice write by Walter George Bradley. This book was released on 2004. Neurology in Clinical Practice available in PDF, EPUB and Kindle. New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.
Magnesium in the Central Nervous System
Magnesium in the Central Nervous System - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Magnesium in the Central Nervous System write by Robert Vink. This book was released on 2011. Magnesium in the Central Nervous System available in PDF, EPUB and Kindle. The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
