Prodrug Design - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Prodrug Design write by Vivekkumar K Redasani. This book was released on 2015-07-07. Prodrug Design available in PDF, EPUB and Kindle. Prodrug Design: Perspectives, Approaches and Applications in Medicinal Chemistry provides a focused overview of this critical area of drug discovery, as that continuous process strives not only to discover new drug compounds but also to modify the existing ones. This valuable primer supports this mission of drug development and its goal of reducing undesired effects and improving therapeutic effectiveness of drug compounds. Providing a unique compilation of data, insightful case studies, and review of existing literature in the area, the book will promote innovation in medicinal and pharmaceutical chemistry research, exploring the limitations of existing drugs and their improvement. Prodrug Design reviews marketed compounds, the safety of promoieties, and a detailed classification of prodrugs organized by therapeutic area for easy reference. Offers unique, detailed overview of Prodrug research and literature Provides detailed chemical structures Includes Prodrug listing by therapeutic area
Recent Advancement in Prodrugs
Recent Advancement in Prodrugs - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Recent Advancement in Prodrugs write by Kamal Shah. This book was released on 2020-05-22. Recent Advancement in Prodrugs available in PDF, EPUB and Kindle. Recent Advancement in Prodrugs Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations. Key features Covers recent advancements in development of prodrugs Presents balanced synthesis and applications of prodrug chemistry Discusses broad spectrum of prodrug categories and outlines industrial applications Reviews prodrugs in cancer nanomedicine, its therapy and treatment Elucidates mathematical models to study the kinetics of prodrugs This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.
Prodrugs and Targeted Delivery
Prodrugs and Targeted Delivery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Prodrugs and Targeted Delivery write by Jarkko Rautio. This book was released on 2011-01-11. Prodrugs and Targeted Delivery available in PDF, EPUB and Kindle. This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.
Physico-Chemical and Computational Approaches to Drug Discovery
Physico-Chemical and Computational Approaches to Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Physico-Chemical and Computational Approaches to Drug Discovery write by Javier Luque. This book was released on 2012-03-31. Physico-Chemical and Computational Approaches to Drug Discovery available in PDF, EPUB and Kindle. Molecular modeling and simulation play a central role in academic and industrial research focused on physico-chemical properties and processes. The efforts carried out in this field have crystallized in a variety of models, simulation methods, and computational techniques that are examining the relationship between the structure, dynamics and functional role of biomolecules and their interactions. In particular, there has been a huge advance in the understanding of the molecular determinants that mediate the interaction between small compounds acting as ligands and their macromolecular targets. This book provides an updated description of the advances experienced in recent years in the field of molecular modeling and simulation of biomolecular recognition, with particular emphasis towards the development of efficient strategies in structure-based drug design.
Design of Prodrugs
Design of Prodrugs - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Design of Prodrugs write by Hans Bundgaard. This book was released on 1985. Design of Prodrugs available in PDF, EPUB and Kindle.
