Prodrugs and Targeted Delivery

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Release : 2011-01-11
Genre : Medical
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Book Rating : 189/5 ( reviews)

Prodrugs and Targeted Delivery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Prodrugs and Targeted Delivery write by Jarkko Rautio. This book was released on 2011-01-11. Prodrugs and Targeted Delivery available in PDF, EPUB and Kindle. This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.

Prodrugs

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Release : 2007-03-12
Genre : Medical
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Book Rating : 82X/5 ( reviews)

Prodrugs - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Prodrugs write by Valentino Stella. This book was released on 2007-03-12. Prodrugs available in PDF, EPUB and Kindle. These volumes represent a comprehensive guide to prodrugs. They guide the reader through the current status of the prodrug concept and its many applications and highlight its many successes in overcoming formulation and delivery of problematic drugs. Replete with examples of approved and marketed prodrugs, these volumes introduce the topic to the novice as well as professional in the design of prodrugs.

Targeted Drug Delivery : Concepts and Design

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Release : 2014-12-08
Genre : Medical
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Book Rating : 550/5 ( reviews)

Targeted Drug Delivery : Concepts and Design - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Targeted Drug Delivery : Concepts and Design write by Padma V. Devarajan. This book was released on 2014-12-08. Targeted Drug Delivery : Concepts and Design available in PDF, EPUB and Kindle. This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

The Organic Chemistry of Drug Design and Drug Action

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Release : 2012-12-02
Genre : Science
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Book Rating : 379/5 ( reviews)

The Organic Chemistry of Drug Design and Drug Action - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Organic Chemistry of Drug Design and Drug Action write by Richard B. Silverman. This book was released on 2012-12-02. The Organic Chemistry of Drug Design and Drug Action available in PDF, EPUB and Kindle. Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

Recent Advancement in Prodrugs

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Release : 2020
Genre : Science
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Book Rating : 275/5 ( reviews)

Recent Advancement in Prodrugs - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Recent Advancement in Prodrugs write by Kamal Shah. This book was released on 2020. Recent Advancement in Prodrugs available in PDF, EPUB and Kindle. Recent Advancement in Prodrugs Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations. Key features Covers recent advancements in development of prodrugs Presents balanced synthesis and applications of prodrug chemistry Discusses broad spectrum of prodrug categories and outlines industrial applications Reviews prodrugs in cancer nanomedicine, its therapy and treatment Elucidates mathematical models to study the kinetics of prodrugs This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.