Protein Interaction Networks - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Interaction Networks write by Aidong Zhang. This book was released on 2009-04-06. Protein Interaction Networks available in PDF, EPUB and Kindle. The analysis of protein-protein interactions is fundamental to the understanding of cellular organization, processes, and functions. Proteins seldom act as single isolated species; rather, proteins involved in the same cellular processes often interact with each other. Functions of uncharacterized proteins can be predicted through comparison with the interactions of similar known proteins. Recent large-scale investigations of protein-protein interactions using such techniques as two-hybrid systems, mass spectrometry, and protein microarrays have enriched the available protein interaction data and facilitated the construction of integrated protein-protein interaction networks. The resulting large volume of protein-protein interaction data has posed a challenge to experimental investigation. This book provides a comprehensive understanding of the computational methods available for the analysis of protein-protein interaction networks. It offers an in-depth survey of a range of approaches, including statistical, topological, data-mining, and ontology-based methods. The author discusses the fundamental principles underlying each of these approaches and their respective benefits and drawbacks, and she offers suggestions for future research.
Protein-Protein Interaction Networks
Protein-Protein Interaction Networks - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein-Protein Interaction Networks write by Stefan Canzar. This book was released on 2019-10-04. Protein-Protein Interaction Networks available in PDF, EPUB and Kindle. This volume explores techniques that study interactions between proteins in different species, and combines them with context-specific data, analysis of omics datasets, and assembles individual interactions into higher-order semantic units, i.e., protein complexes and functional modules. The chapters in this book cover computational methods that solve diverse tasks such as the prediction of functional protein-protein interactions; the alignment-based comparison of interaction networks by SANA; using the RaptorX-ComplexContact webserver to predict inter-protein residue-residue contacts; the docking of alternative confirmations of proteins participating in binary interactions and the visually-guided selection of a docking model using COZOID; the detection of novel functional units by KeyPathwayMiner and how PathClass can use such de novo pathways to classify breast cancer subtypes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary hardware- and software, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Protein-Protein Interaction Networks: Methods and Protocols is a valuable resource for both novice and expert researchers who are interested in learning more about this evolving field.
Biological Data Mining in Protein Interaction Networks
Biological Data Mining in Protein Interaction Networks - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Biological Data Mining in Protein Interaction Networks write by Li, Xiao-Li. This book was released on 2009-05-31. Biological Data Mining in Protein Interaction Networks available in PDF, EPUB and Kindle. "The goal of this book is to disseminate research results and best practices from cross-disciplinary researchers and practitioners interested in, and working on bioinformatics, data mining, and proteomics"--Provided by publisher.
The Autoimmune Diseases
The Autoimmune Diseases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Autoimmune Diseases write by Noel R. Rose. This book was released on 1998. The Autoimmune Diseases available in PDF, EPUB and Kindle. The Autoimmune Diseases comprehensively describes the clinical expressions of all known autoimmune diseases, as well as the experimental bases of autoimmunity and failure of tolerance. The scientific chapters include mechanisms of natural tolerance, the genetic basis of autoimmunity, the significance of apoptosis, the influence of cytokines, environmental influences, and experimental models. The clinical chapters cover autoimmune endocrine deficiencies, insulin-dependent diabetes, rheumatic disorders, neurological diseases, and diseases of the blood, skin, eye, kidney, and liver.
Protein-protein Interactions and Networks
Protein-protein Interactions and Networks - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein-protein Interactions and Networks write by Anna Panchenko. This book was released on 2010-04-06. Protein-protein Interactions and Networks available in PDF, EPUB and Kindle. The biological interactions of living organisms, and protein-protein interactions in particular, are astonishingly diverse. This comprehensive book provides a broad, thorough and multidisciplinary coverage of its field. It integrates different approaches from bioinformatics, biochemistry, computational analysis and systems biology to offer the reader a comprehensive global view of the diverse data on protein-protein interactions and protein interaction networks.
